Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | CASP2 | P42575 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31285850 | 0.81 | KMT2A (0.42) | EPHX2HSD17B3MEN1KMT2ABRPF1 | |
| SCHEMBL8793695 | 0.81 | KMT2A (0.42) | EPHX2HSD17B3MEN1KMT2ABRPF1 | |
| SCHEMBL6690571 | 0.81 | BRPF1 (0.35) | EPHX2HSD17B3HDAC2HDAC8HDAC6 | |
| SCHEMBL6175819 | 0.79 | PTGS1 (0.42) | EPHX2HSD17B3HDAC2HDAC8HDAC6 | |
| SCHEMBL6450576 | 0.75 | BRPF1 (0.44) | EPHX2HSD17B3MEN1KMT2ABRPF1 | |
| SCHEMBL14309648 | 0.73 | SLC6A2 (0.52) | MAPK1ALDH1A1 | |
| SCHEMBL9304274 | 0.73 | EPHX2 (0.57) | EPHX2HDAC2HDAC8HDAC6KMT2A | |
| SCHEMBL9366970 | 0.72 | ATM (0.32) | EPHX2HSD17B3HDAC2HDAC8HDAC6 | |
| SCHEMBL9366994 | 0.72 | ATM (0.32) | EPHX2HSD17B3HDAC2HDAC8HDAC6 | |
| SCHEMBL9868798 | 0.72 | GRIA2 (0.44) | EPHX2HSD17B3MEN1KMT2ABRPF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004005407-A2 | TETRA-AZAPENTAMETHINE AND USE THEREOF FOR DYEING KERATINOUS FIBERS | L'OREAL (FR) | 2004-01-15 | — | — | WO | claimed |
| EP-1378544-A2 | Tetraaza-pentamethine derivatives and their application for dyeing keratinous fibres | L'OREAL (FR) | 2004-01-07 | — | — | EP | claimed |
| WO-2004005407-A2 | TETRA-AZAPENTAMETHINE AND USE THEREOF FOR DYEING KERATINOUS FIBERS | L'OREAL (FR) | 2004-01-15 | — | — | WO | disclosed |
| EP-1378544-A2 | Tetraaza-pentamethine derivatives and their application for dyeing keratinous fibres | L'OREAL (FR) | 2004-01-07 | — | — | EP | disclosed |