Hydrochloric Acid

Hydrochloric Acid

SCHEMBL6693835

CC1=C(Cc2ccccc2)c2ccccc2C1[Zr+2][SiH](C)C.[Cl-].[Cl-]

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
MAPK1 P28482 1/20 0.33
HIF1A Q16665 1/20 0.33
CALM1 P0DP23 1/20 0.31
TBXAS1 P24557 1/20 0.31
LTA4H P09960 1/20 0.31
HTR6 P50406 2/20 0.31
NPC1 O15118 1/20 0.30
HPGD P15428 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7643268 0.73 GPR3 (0.41) CYP1A2
Hydrochloric Acid SCHEMBL27182290 0.68 MAP2K7 (0.30)
SCHEMBL28372193 0.67 CYP1A2 (0.32) CYP1A2CYP2C9MAPK1HIF1ACALM1
Hydrochloric Acid SCHEMBL27182326 0.66 BCHE (0.31)
Fluoride Ion SCHEMBL27182220 0.65 MAP2K7 (0.30)
Bromide SCHEMBL27203207 0.65 MAP2K7 (0.30)
Iodide SCHEMBL27182250 0.65 MAP2K7 (0.30)
SCHEMBL31619970 0.65 MEN1 (0.40) HTR6HPGDSMN1; SMN2
SCHEMBL31619972 0.65 MEN1 (0.40) HTR6HPGDSMN1; SMN2
SCHEMBL31619977 0.63 HTR2A (0.33) HTR6HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3621996-A1 CATALYST SYSTEMS AND PROCESSES FOR USING THE SAME ExxonMobil Chemical Patents Inc. (US) 2020-03-18 EP claimed
US-20180327524-A1 Catalyst Systems and Processes for Using the Same UNIVATION TECHNOLOGIES LLC 2018-11-15 US claimed
WO-2018208414-A1 CATALYST SYSTEMS AND PROCESSES FOR USING THE SAME EXXONMOBIL CHEMICAL PATENTS INC. (US) 2018-11-15 WO claimed
EP-3621996-B1 CATALYST SYSTEMS AND PROCESSES FOR USING THE SAME UNIVATION TECH LLC (US) 2023-01-18 EP disclosed
US-20210163639-A1 CATALYST SYSTEMS AND PROCESSES FOR USING THE SAME UNIVATION TECHNOLOGIES, LLC (US) 2021-06-03 US disclosed
US-10947329-B2 Catalyst systems and processes for using the same UNIVATION TECHNOLOGIES, LLC (US) 2021-03-16 US disclosed
EP-3621996-A1 CATALYST SYSTEMS AND PROCESSES FOR USING THE SAME ExxonMobil Chemical Patents Inc. (US) 2020-03-18 EP disclosed
CN-110770265-A Catalyst system and method of use thereof 埃克森美孚化学专利公司 2020-02-07 CN disclosed
US-20180327524-A1 Catalyst Systems and Processes for Using the Same UNIVATION TECHNOLOGIES LLC 2018-11-15 US disclosed
WO-2018208414-A1 CATALYST SYSTEMS AND PROCESSES FOR USING THE SAME EXXONMOBIL CHEMICAL PATENTS INC. (US) 2018-11-15 WO disclosed
US-6800704-B2 NARROW COMPOSITION DISTRIBUTIONS, LOW MELT INDEX RATIOS, AND HIGH MELT STRENGTH EXXONMOBIL CHEMICAL PATENTS INC. 2004-10-05 US disclosed
EP-0912618-B1 OLEFIN POLYMERIZATION PROCESS WITH ALKYL-SUBSTITUTED METALLOCENES EXXONMOBIL CHEM PATENTS INC (US) 2001-11-28 EP disclosed