Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.51 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | CASP7 | P55210 | 2/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8571050 | 0.80 | MET (0.51) | CSNK2A2CSNK2BCSNK2A1MCL1ALDH1A1 | |
| SCHEMBL29391372 | 0.78 | MCL1 (0.55) | MCL1HSD17B3CYP1A2ALDH1A1HPGD | |
| SCHEMBL565580 | 0.78 | MCL1 (0.55) | MCL1HSD17B3CYP1A2ALDH1A1HPGD | |
| SCHEMBL8639385 | 0.74 | ATP1A1 (0.42) | CSNK2A2CSNK2BCSNK2A1CYP1A2CYP1A1 | |
| SCHEMBL669385 | 0.74 | MCL1 (0.56) | MCL1ALDH1A1HPGDHSD17B10CASP1 | |
| SCHEMBL28065503 | 0.73 | CSNK2A2 (0.73) | CSNK2A2CSNK2BCSNK2A1MCL1HSD17B3 | |
| Phosphoric Acid SCHEMBL1934555 | 0.73 | MCL1 (0.50) | MCL1HSD17B3CYP1A2ALDH1A1HPGD | |
| SCHEMBL875961 | 0.71 | KDM4E (0.39) | MCL1ALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL8564999 | 0.70 | KDM4E (0.38) | MCL1ALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL14925107 | 0.70 | ERN1 (0.51) | CSNK2A2CSNK2BCSNK2A1MCL1HSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830912-A | Derivatives of 6,8-difluoro-7-hydroxycoumarin | MOLECULAR PROBES, INC. (US) | 1998-11-03 | — | — | US | disclosed |