Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MPI | P34949 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 4/20 | 0.43 |
| ▸ | BTK | Q06187 | 4/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6696450 | 0.84 | RXFP1 (0.60) | RXFP1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6701678 | 0.81 | RXFP1 (0.72) | RXFP1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL4356068 | 0.79 | RXFP1 (0.55) | RXFP1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL16679725 | 0.78 | RXFP1 (0.64) | RXFP1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6693381 | 0.77 | P2RX1 (0.55) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL6696124 | 0.75 | RXFP1 (0.57) | RXFP1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL4347945 | 0.73 | RXFP1 (0.59) | RXFP1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL4343726 | 0.73 | RXFP1 (0.59) | RXFP1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6693899 | 0.73 | P2RX1 (0.54) | RXFP1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6690783 | 0.71 | RXFP1 (0.44) | RXFP1ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040009973-A1 | Phenylenediamine derivatives N-substituted with benzyl- or heteroarylmethyl- groups | 4SC AG (DE) | 2004-01-15 | — | — | US | disclosed |
| WO-2003076388-A2 | BIS-ANILINE DERIVATIVES USEFUL AS POTASSIUM CHANNELS MODULATORS | 4SC AG (DE) | 2003-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040009973-A1 | Phenylenediamine derivatives N-substituted with benzyl- or heteroarylmethyl- groups | PAH, PNMT, OPRM1 | RXFP1 2157/4885ALDH1A1 458/4885MAPT 3951/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.