Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | MPI | P34949 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | LCK | P06239 | 4/20 | 0.51 |
| ▸ | BTK | Q06187 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16679725 | 0.89 | RXFP1 (0.64) | RXFP1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6701678 | 0.89 | RXFP1 (0.72) | RXFP1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6690783 | 0.87 | RXFP1 (0.44) | RXFP1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6696124 | 0.85 | RXFP1 (0.57) | RXFP1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL4343726 | 0.84 | RXFP1 (0.59) | RXFP1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL4347945 | 0.84 | RXFP1 (0.59) | RXFP1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6693874 | 0.84 | RXFP1 (0.52) | RXFP1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL4356068 | 0.83 | RXFP1 (0.55) | RXFP1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL11510231 | 0.79 | GAA (0.53) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL6691456 | 0.79 | MEN1 (0.49) | RXFP1MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040009973-A1 | Phenylenediamine derivatives N-substituted with benzyl- or heteroarylmethyl- groups | 4SC AG (DE) | 2004-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040009973-A1 | Phenylenediamine derivatives N-substituted with benzyl- or heteroarylmethyl- groups | PAH, PNMT, OPRM1 | RXFP1 2157/4885MAPT 3951/4885ALDH1A1 458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.