Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6692057 | 1.00 | ROCK2 (0.30) | ROCK2ROCK1 | |
| SCHEMBL6286402 | 0.81 | — | — | |
| SCHEMBL6258397 | 0.81 | — | — | |
| SCHEMBL8062803 | 0.79 | FKBP1A (0.33) | — | |
| SCHEMBL12632024 | 0.79 | FKBP1A (0.33) | — | |
| SCHEMBL15863029 | 0.78 | — | — | |
| SCHEMBL18159815 | 0.76 | FKBP1A (0.31) | — | |
| SCHEMBL32662977 | 0.75 | FKBP1A (0.31) | — | |
| SCHEMBL6244856 | 0.74 | CYP1A2 (0.44) | — | |
| SCHEMBL5516925 | 0.74 | NCF1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138272-A1 | 1,4-Substituted cyclohexane derivatives | UNIVERSITE DE MONTREAL (CA) | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138272-A1 | 1,4-Substituted cyclohexane derivatives | ROCK1, RAC1, KSR1 | ROCK2 11/4885ROCK1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.