Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1D | Q01668 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1222086 | 0.72 | EDNRA (0.33) | CACNA1DMAPK1 | |
| SCHEMBL7406805 | 0.71 | TSHR (0.39) | CACNA1D | |
| SCHEMBL3780105 | 0.69 | MAPT (0.33) | CACNA1D | |
| SCHEMBL9842403 | 0.69 | ELANE (0.33) | — | |
| SCHEMBL9461568 | 0.68 | CACNA1D (0.35) | CACNA1D | |
| SCHEMBL4178861 | 0.65 | PPARG (0.35) | — | |
| SCHEMBL5011863 | 0.64 | KDM4E (0.32) | CACNA1D | |
| SCHEMBL9842447 | 0.64 | PPARG (0.34) | — | |
| SCHEMBL9664200 | 0.63 | TP53 (0.32) | — | |
| SCHEMBL9842547 | 0.63 | CACNA1D (0.33) | CACNA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014159772-A2 | INHIBITION OF THE TOXIC EFFECTS OF ISLET AMYLOID FORMATION BY FLURIPROFEN AND FLURIPROFEN DERIVATIVES | THE RESEARCH FOUNDATION FOR THE STATW UNIVERSITY OF NEW YORK (US) | 2014-10-02 | — | — | WO | disclosed |
| WO-2004091522-A2 | METHOD FOR TREATING NEURODEGENERATIVE DISORDERS | MYRIAD GENETICS, INC. (US) | 2004-10-28 | — | — | WO | disclosed |
| EP-0979226-A1 | ISOXAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-02-16 | — | — | EP | disclosed |
| WO-1998047880-A1 | ISOXAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-10-29 | — | — | WO | disclosed |