SCHEMBL9664200

SCHEMBL9664200

CCc1ccc(C(C)C2(C(C)c3ccc(CC)cc3)C=CC(c3ccccc3)C(F)=C2)cc1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.32
KDM1A O60341 1/20 0.32
CYP19A1 P11511 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9663287 0.90 HTR2A (0.33)
SCHEMBL9842403 0.68 ELANE (0.33)
SCHEMBL9842547 0.65 CACNA1D (0.33)
SCHEMBL8393880 0.64 CACNA1D (0.30)
SCHEMBL9842625 0.63 HTR2A (0.30)
SCHEMBL6694686 0.63 CACNA1D (0.30)
SCHEMBL9842466 0.63 MMP2 (0.31) KDM1A
Isopropylbenzene SCHEMBL7651427 0.61 TP53 (0.56) TP53CYP19A1
SCHEMBL444227 0.61 TP53 (0.56) TP53CYP19A1
SCHEMBL6546869 0.61 TP53 (0.56) TP53CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5093026-A Liquid crystals MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1992-03-03 US disclosed
WO-1990008756-A1 DIPHENYLETHANES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1990-08-09 WO disclosed