Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 5/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3043072 | 1.00 | MAOA (0.43) | MAOATMEM97SIGMAR1HTR6F10 | |
| SCHEMBL3042951 | 0.89 | TMEM97 (0.37) | TMEM97SIGMAR1HTR6F10HDAC6 | |
| SCHEMBL3043362 | 0.87 | MAOA (0.46) | MAOAHTR6F10 | |
| SCHEMBL5795451 | 0.87 | MAOA (0.46) | MAOAHTR6F10 | |
| SCHEMBL3039459 | 0.82 | MAOA (0.45) | MAOAHTR6F10 | |
| SCHEMBL3046390 | 0.78 | F10 (0.39) | MAOAHTR6F10 | |
| SCHEMBL14334714 | 0.76 | MAOA (0.47) | MAOATMEM97SIGMAR1HTR6F10 | |
| SCHEMBL14334493 | 0.76 | F10 (0.45) | MAOATMEM97SIGMAR1HTR6F10 | |
| SCHEMBL6040312 | 0.75 | MAOA (0.54) | MAOAF10 | |
| SCHEMBL14334647 | 0.74 | HTR6 (0.62) | MAOAHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478629-A1 | N-ARYL-2-OXAZOLIDINONE-5-CARBOXAMIDES AND THEIR DERIVATIVES AND THEIR USE AS ANTIBACTERIALS | PHARMACIA & UPJOHN COMPANY (US) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003072553-A1 | N-ARYL-2-OXAZOLIDINONE-5-CARBOXAMIDES AND THEIR DERIVATES AND THEIR USE AS ANTIBACTERIALS | PHARMACIA & UPJOHN COMPANY (US) | 2003-09-04 | — | — | WO | disclosed |