Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8357937 | 0.90 | KIF11 (0.44) | SMN1; SMN2L3MBTL1KMT2AMEN1CHRM2 | |
| SCHEMBL439212 | 0.76 | KIF11 (0.46) | TSHRCYP11B1CYP11B2KIF11CYP1A2 | |
| SCHEMBL6351579 | 0.75 | L3MBTL1 (0.41) | SMN1; SMN2L3MBTL1KMT2AMEN1CHRM2 | |
| SCHEMBL31324682 | 0.73 | L3MBTL1 (0.54) | SMN1; SMN2L3MBTL1KMT2AMEN1CHRM2 | |
| SCHEMBL13053153 | 0.73 | L3MBTL1 (0.54) | SMN1; SMN2L3MBTL1KMT2AMEN1CHRM2 | |
| SCHEMBL4327683 | 0.73 | L3MBTL1 (0.54) | SMN1; SMN2L3MBTL1KMT2AMEN1CHRM2 | |
| SCHEMBL29410666 | 0.71 | L3MBTL1 (0.78) | SMN1; SMN2L3MBTL1KMT2AMEN1CHRM2 | |
| SCHEMBL8392798 | 0.71 | SMN1; SMN2 (0.52) | SMN1; SMN2L3MBTL1KMT2AMEN1CHRM2 | |
| SCHEMBL912495 | 0.71 | L3MBTL1 (0.78) | SMN1; SMN2L3MBTL1KMT2AMEN1CHRM2 | |
| SCHEMBL11171434 | 0.71 | SMN1; SMN2 (0.47) | SMN1; SMN2L3MBTL1KMT2AMEN1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3553083-B2 | — | — | 2004-08-11 | — | — | JP | claimed |
| EP-0852494-A2 | PERIPHERALLY ACTIVE ANTI-HYPERALGESIC OPIATES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-07-15 | — | — | EP | claimed |
| WO-1997009973-A2 | PERIPHERALLY ACTIVE ANTI-HYPERALGESIC OPIATES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-03-20 | — | — | WO | claimed |