Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR3 | O60755 | 3/20 | 0.71 |
| ▸ | NR2F2 | P24468 | 3/20 | 0.71 |
| ▸ | TNF | P01375 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | EDNRA | P25101 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PDE6D | O43924 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.49 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6225425 | 0.99 | GALR3 (0.69) | GALR3NR2F2TNFRAB9AHDAC1 | |
| SCHEMBL6225426 | 0.97 | GALR3 (0.67) | GALR3NR2F2TNFRAB9AHDAC1 | |
| SCHEMBL10443491 | 0.86 | TNF (0.68) | GALR3NR2F2TNFRAB9AHDAC1 | |
| SCHEMBL10443492 | 0.85 | TNF (0.67) | GALR3NR2F2TNFRAB9AHDAC1 | |
| SCHEMBL12771519 | 0.83 | GALR3 (1.00) | GALR3NR2F2TNFRAB9AHDAC1 | |
| SCHEMBL9260111 | 0.80 | TNF (0.77) | GALR3NR2F2TNFRAB9AHDAC1 | |
| SCHEMBL8396864 | 0.80 | PPARG (0.72) | GALR3NR2F2TNFRAB9AHDAC1 | |
| SCHEMBL6833621 | 0.80 | TNF (0.81) | GALR3NR2F2TNFRAB9AHDAC1 | |
| SCHEMBL231295 | 0.80 | TNF (1.00) | GALR3NR2F2TNFRAB9AHDAC1 | |
| Chlormidazole SCHEMBL148113 | 0.79 | GALR3 (1.00) | GALR3NR2F2TNFRAB9AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040229874-A1 | 5HT7 Antagonists and inverse agonists | PFIZER INC. | 2004-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040229874-A1 | 5HT7 Antagonists and inverse agonists | HTR7, HTR1A, HTR1B | GALR3 167/4885NR2F2 2389/4885TNF 4100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.