SCHEMBL669563

SCHEMBL669563

CC(Nc1ccc(C(=O)c2ccccc2)cc1)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK13 O15264 1/20 0.61
MAPK12 P53778 1/20 0.61
MAPK11 Q15759 1/20 0.61
MAPK14 Q16539 1/20 0.61
ALDH1A1 P00352 8/20 0.60
RAB9A P51151 4/20 0.60
HPGD P15428 4/20 0.60
SMN1; SMN2 Q16637 4/20 0.60
HTT P42858 1/20 0.60
NPSR1 Q6W5P4 1/20 0.60
L3MBTL1 Q9Y468 1/20 0.56
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
NPC1 O15118 1/20 0.53
LMNA P02545 2/20 0.50
FFAR1 O14842 1/20 0.49
SRD5A2 P31213 1/20 0.48
PTGS1 P23219 3/20 0.47
PTGS2 P35354 3/20 0.47
MAPT P10636 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL669564 1.00 MAPK13 (0.61) MAPK13MAPK12MAPK11MAPK14ALDH1A1
SCHEMBL1615179 0.85 ALDH1A1 (0.65) MAPK13MAPK12MAPK11MAPK14ALDH1A1
SCHEMBL11453059 0.85 PTGS1 (0.55) MAPK13MAPK12MAPK11MAPK14ALDH1A1
SCHEMBL11453058 0.85 PTGS1 (0.55) MAPK13MAPK12MAPK11MAPK14ALDH1A1
SCHEMBL33928 0.85 TDP1 (0.56) ALDH1A1HPGDSMN1; SMN2L3MBTL1MEN1
SCHEMBL1531678 0.85 TDP1 (0.56) ALDH1A1HPGDSMN1; SMN2L3MBTL1MEN1
SCHEMBL1330911 0.85 TDP1 (0.56) ALDH1A1HPGDSMN1; SMN2L3MBTL1MEN1
SCHEMBL1331551 0.85 TDP1 (0.56) ALDH1A1HPGDSMN1; SMN2L3MBTL1MEN1
SCHEMBL33927 0.85 TDP1 (0.56) ALDH1A1HPGDSMN1; SMN2L3MBTL1MEN1
Water SCHEMBL11454954 0.83 PTGS1 (0.54) MAPK13MAPK12MAPK11MAPK14ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3908306-A1 PHOSPHATASE BINDING COMPOUNDS AND METHODS OF USING SAME Yale University (US) 2021-11-17 EP claimed
WO-2020146470-A1 Phosphatase Binding Compounds and Methods of Using Same YALE UNIVERSITY (US) 2020-07-16 WO claimed
EP-4569331-A1 DE NOVO PORES Oxford Nanopore Technologies PLC (GB) 2025-06-18 EP disclosed
CN-119678047-A From the head hole 牛津纳米孔科技公开有限公司 2025-03-21 CN disclosed
US-20250066424-A1 NOVEL PROTEIN PORES VIB VZW (BE) 2025-02-27 US disclosed
EP-4508203-A2 NOVEL MODIFIED PROTEIN PORES AND ENZYMES Oxford Nanopore Technologies PLC (GB) 2025-02-19 EP disclosed
CN-119192308-A Novel protein pores 弗拉芒区生物技术研究所 2024-12-27 CN disclosed
CN-119137267-A Novel modified protein pores and enzymes 牛津纳米孔科技公开有限公司 2024-12-13 CN disclosed
US-12084477-B2 Protein pores VIB VZW (BE) 2024-09-10 US disclosed
US-11945840-B2 Protein pores VIB VZW (BE) 2024-04-02 US disclosed
WO-2024033447-A1 DE NOVO PORES OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2024-02-15 WO disclosed
US-20090221483-A1 Antimicrobial Cathelicidin Peptides KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) 2009-09-03 US disclosed
EP-2046814-A2 MINIMIZED SMALL PEPTIDES WITH HIGH AFFINITY FOR FACTOR VIII AND FACTOR VIII-LIKE PROTEINS Technische Universität München (DE) 2009-04-15 EP disclosed
WO-2008003707-A2 MINIMIZED SMALL PEPTIDES WITH HIGH AFFINITY FOR FACTOR VIII AND FACTOR VIII-LIKE PROTEINS Technische Universität München (DE) 2008-01-10 WO disclosed
EP-0730605-A1 SUBSTITUTED DI- AND TRIPEPTIDE INHIBITORS OF PROTEIN:FARNESYL TRANSFERASE WARNER-LAMBERT COMPANY (US) 1996-09-11 EP disclosed
EP-0725790-A1 SUBSTITUTED TETRA- AND PENTAPEPTIDE INHIBITORS OF PROTEIN:FARNESYL TRANSFERASE PARKE DAVIS & COMPANY (US) 1996-08-14 EP disclosed
WO-1996017861-A1 SUBSTITUTED TETRA- AND PENTAPEPTIDE INHIBITORS OF PROTEIN:FARNESYL TRANSFERASE WARNER-LAMBERT COMPANY (US) 1996-06-13 WO disclosed
WO-1995012612-A1 SUBSTITUTED DI- AND TRIPEPTIDE INHIBITORS OF PROTEIN:FARNESYL TRANSFERASE WARNER-LAMBERT COMPANY (US) 1995-05-11 WO disclosed
WO-1995011917-A1 SUBSTITUTED TETRA- AND PENTAPEPTIDE INHIBITORS OF PROTEIN:FARNESYL TRANSFERASE PARKE, DAVIS & COMPANY (US) 1995-05-04 WO disclosed
EP-0237918-A2 N-substituted amino-alcanoic acids, process for their preparation, their use and pharmaceutical preparations based on these compounds HOECHST AKTIENGESELLSCHAFT (DE) 1987-09-23 EP disclosed