SCHEMBL6695737

SCHEMBL6695737

C=C(C)c1ccc(OC(C)(OCCCC)C(C)(C)C)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.35
RAB9A P51151 2/20 0.35
TP53 P04637 2/20 0.35
TSHR P16473 2/20 0.35
HDAC3 O15379 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC2 Q92769 1/20 0.35
PLA2G4B P0C869 2/20 0.34
PSEN1 P49768 2/20 0.34
PSEN2 P49810 2/20 0.34
APH1B Q8WW43 2/20 0.34
NCSTN Q92542 2/20 0.34
APH1A Q96BI3 2/20 0.34
PSENEN Q9NZ42 2/20 0.34
RARB P10826 3/20 0.33
LMNA P02545 2/20 0.33
SLC2A1 P11166 1/20 0.33
NPC1 O15118 1/20 0.33
MAPT P10636 1/20 0.33
ALOX15 P16050 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6690539 0.97 TP53 (0.39) GAARAB9ATP53TSHRPLA2G4B
SCHEMBL6694229 0.96 TP53 (0.41) GAARAB9ATP53TSHRPLA2G4B
SCHEMBL6689024 0.93 L3MBTL1 (0.33) HDAC3HDAC1HDAC2PSEN1PSEN2
SCHEMBL6694535 0.86 ABCB11 (0.33) TSHRMAPTCYP1A2
SCHEMBL6690565 0.85 TSHR (0.36) GAARAB9ATP53TSHRHDAC3
SCHEMBL6697849 0.84 GAA (0.36) GAARAB9ATP53TSHRHDAC3
SCHEMBL6689017 0.82 TP53 (0.41) GAARAB9ATP53TSHRPLA2G4B
SCHEMBL6697798 0.81 GAA (0.34) GAARAB9ATP53TSHRHDAC3
SCHEMBL6694140 0.81 TP53 (0.43) GAARAB9ATP53TSHRPLA2G4B
SCHEMBL6691454 0.81 ELANE (0.35) GAARAB9ATP53TSHRHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0959389-B1 Diazodisulfone compound and radiation-sensitive resin composition JSR CORP (JP) 2004-03-31 EP disclosed
US-6143460-A PHOTOACID GENERATOR PROVIDING IMPROVED PHOTORESIST RESOLUTION JSR CORPORATION (JP) 2000-11-07 US disclosed
EP-0959389-A1 Diazodisulfone compound and radiation-sensitive resin composition JSR Corporation (JP) 1999-11-24 EP disclosed