Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | PKLR | P30613 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3077251 | 0.84 | ALDH1A1 (0.57) | ALDH1A1PKMPOLBLMNAMAPT | |
| SCHEMBL6925923 | 0.84 | ALDH1A1 (0.58) | ALDH1A1PKMPOLBLMNAMAPT | |
| SCHEMBL6690056 | 0.83 | POLB (0.51) | ALDH1A1PKMUSP2POLBLMNA | |
| SCHEMBL3069113 | 0.83 | ALDH1A1 (0.60) | ALDH1A1PKMPOLBLMNAMAPT | |
| SCHEMBL17331314 | 0.81 | ALDH1A1 (0.62) | ALDH1A1POLBLMNAMAPTRAB9A | |
| SCHEMBL17331339 | 0.81 | ALDH1A1 (0.65) | ALDH1A1PKMUSP2POLBLMNA | |
| SCHEMBL17331325 | 0.80 | ALDH1A1 (0.62) | ALDH1A1POLBLMNAMAPTSMN1; SMN2 | |
| SCHEMBL3069441 | 0.80 | TSHR (0.60) | ALDH1A1LMNAHSD17B10L3MBTL1SMN1; SMN2 | |
| SCHEMBL3058528 | 0.77 | ALDH1A1 (0.50) | ALDH1A1PKMUSP2LMNAPKLR | |
| SCHEMBL6923759 | 0.76 | POLB (0.57) | ALDH1A1PKMPOLBLMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004074438-A2 | CCR8 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-09-02 | — | — | WO | disclosed |