Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3069679 | 0.91 | ALDH1A1 (0.54) | ALDH1A1LMNAPOLBPKMRAB9A | |
| SCHEMBL6925605 | 0.87 | POLB (0.59) | ALDH1A1LMNAPOLBPKMRAB9A | |
| SCHEMBL3077251 | 0.87 | ALDH1A1 (0.57) | ALDH1A1LMNAPOLBPKMRAB9A | |
| SCHEMBL17331325 | 0.86 | ALDH1A1 (0.62) | ALDH1A1LMNAPOLBGAAMAPT | |
| SCHEMBL3069113 | 0.85 | ALDH1A1 (0.60) | ALDH1A1LMNAPOLBPKMRAB9A | |
| SCHEMBL6695770 | 0.84 | ALDH1A1 (0.56) | ALDH1A1LMNAPOLBPKMRAB9A | |
| SCHEMBL17331314 | 0.83 | ALDH1A1 (0.62) | ALDH1A1LMNAPOLBRAB9AGAA | |
| SCHEMBL17331339 | 0.83 | ALDH1A1 (0.65) | ALDH1A1LMNAPOLBPKMGAA | |
| SCHEMBL6923759 | 0.82 | POLB (0.57) | ALDH1A1LMNAPOLBPKMRAB9A | |
| SCHEMBL6922338 | 0.81 | POLB (0.56) | ALDH1A1LMNAPOLBPKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073619-A2 | CCR8 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-09-02 | — | — | WO | disclosed |