SCHEMBL7150447

SCHEMBL7150447

NC[C@H](O)c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.68
NPC1 O15118 2/20 0.57
TAAR1 Q96RJ0 2/20 0.53
HTR3A P46098 1/20 0.53
TSHR P16473 1/20 0.53
NFKB1 P19838 1/20 0.53
HIF1A Q16665 1/20 0.53
KDM4E B2RXH2 3/20 0.52
LOXL2 Q9Y4K0 1/20 0.52
ALOX15 P16050 1/20 0.52
APEX1 P27695 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
CA12 O43570 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CA9 Q16790 1/20 0.49
CA14 Q9ULX7 1/20 0.49
MAPT P10636 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL334438 1.00 ALDH1A1 (0.68) ALDH1A1NPC1TAAR1HTR3ATSHR
SCHEMBL4942727 1.00 ALDH1A1 (0.68) ALDH1A1NPC1TAAR1HTR3ATSHR
Hydrochloric Acid SCHEMBL26098210 0.98 ALDH1A1 (0.66) ALDH1A1NPC1TAAR1HTR3ATSHR
SCHEMBL6695879 0.85 ALDH1A1 (0.64) ALDH1A1NPC1KDM4ELOXL2MEN1
SCHEMBL1983480 0.84 ALDH1A1 (0.72) ALDH1A1NPC1TSHRKDM4EMEN1
SCHEMBL18913904 0.84 ALDH1A1 (0.72) ALDH1A1NPC1TSHRKDM4EMEN1
SCHEMBL2368297 0.84 ALDH1A1 (0.72) ALDH1A1NPC1TSHRKDM4EMEN1
SCHEMBL240466 0.84 ALDH1A1 (0.72) ALDH1A1NPC1TSHRKDM4EMEN1
SCHEMBL28436171 0.82 ALDH1A1 (0.70) ALDH1A1NPC1TSHRKDM4EMEN1
SCHEMBL1023275 0.82 ALDH1A1 (0.70) ALDH1A1NPC1TSHRKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4713020-A2 DRUG-LINKERS AND DRUG CONJUGATES Solve Therapeutics, Inc. (US) 2026-03-25 EP disclosed
CN-121586589-A Drug linkers and drug conjugates 索尔夫治疗公司 2026-02-27 CN disclosed
US-20260007762-A1 ANTI-ROR2 ANTIBODY-DRUG CONJUGATES SOLVE THERAPEUTICS, INC. (US) 2026-01-08 US disclosed
WO-2024243085-A2 CONJUGATES AND USES THEREOF SOLVE THERAPEUTICS, INC. (US) 2024-11-28 WO disclosed
US-7666849-B2 ligands that are designed to specifically kill or inhibit the growth of any target organism RIB-X PHARMACEUTICALS, INC. (US) 2010-02-23 US disclosed
US-20030143701-A1 Processes for producing optically active 2-amino-1-phenylethanol derivatives DAICEL CHEMICAL INDUSTRIES, LTD. 2003-07-31 US disclosed
EP-0924194-B1 Processes for producing optically active 2-amino-1-phenylethanol derivatives DAICEL CHEM (JP) 2003-05-14 EP disclosed
US-6528686-B1 Reacting primary amine and ketone functionalized derivatives; catalytically reducing DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2003-03-04 US disclosed
EP-0924193-B1 Processes for producing optically active 2-amino-1-phenylethanol derivatives DAICEL CHEM (JP) 2003-02-19 EP disclosed
EP-0939134-B1 Processes for producing optically active 2-amino-1-phenylethanol derivatives DAICEL CHEM (JP) 2002-09-11 EP disclosed
US-6114582-A DECYCLIZATION TO FORM A CHEMICAL INTERMEDIATE FOR PRODUCING AN ANTI-OBESITY AGENT AND ANTIDIABETIC AGENT DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2000-09-05 US disclosed
EP-0654534-B1 Processes for producing optically active 2-amino-1-phenylethanol derivatives DAICEL CHEM (JP) 2000-03-01 EP disclosed
EP-0939134-A1 Processes for producing optically active 2-amino-1-phenylethanol derivatives DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1999-09-01 EP disclosed
EP-0924193-A1 Processes for producing optically active 2-amino-1-phenylethanol derivatives DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1999-06-23 EP disclosed
EP-0924194-A2 Processes for producing optically active 2-amino-1-phenylethanol derivatives DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1999-06-23 EP disclosed
US-5811293-A CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1998-09-22 US disclosed
US-5629200-A MICROORGANISM DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1997-05-13 US disclosed
EP-0654534-A2 Processes for producing optically active 2-amino-1-phenylethanol derivatives DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1995-05-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260007762-A1 ANTI-ROR2 ANTIBODY-DRUG CONJUGATES RORB, RORA, RORC ALDH1A1 602/4885NPC1 1234/4885TAAR1 760/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.