Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | VNN1 | O95497 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | GHSR | Q92847 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6702001 | 0.81 | MTNR1A (0.59) | KMT2AMEN1MAPTCHRNB2CHRNA4 | |
| SCHEMBL6702025 | 0.79 | KMT2A (0.51) | KMT2AMEN1MAPTCHRNB2CHRNA4 | |
| SCHEMBL6703743 | 0.79 | MEN1 (0.51) | KMT2AMEN1MAPTCHRNB2CHRNA4 | |
| SCHEMBL6703871 | 0.79 | CA12 (0.52) | KMT2AMEN1MAPTCHRNB2CHRNA4 | |
| SCHEMBL6700488 | 0.79 | KMT2A (0.51) | KMT2AMEN1MAPTCHRNB2CHRNA4 | |
| SCHEMBL6702035 | 0.78 | KMT2A (0.55) | KMT2AMEN1MAPTCHRNB2CHRNA4 | |
| SCHEMBL6699071 | 0.76 | KMT2A (0.59) | KMT2AMEN1MAPTCHRNB2CHRNA4 | |
| SCHEMBL6702167 | 0.75 | TDP1 (0.53) | KMT2AMEN1MAPTCHRNB2CHRNA4 | |
| SCHEMBL6696307 | 0.75 | MEN1 (0.62) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL1709278 | 0.75 | MEN1 (0.57) | KMT2AMEN1MAPTCHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040044037-A1 | Amidino-urea serotonin receptor ligands and compositions, their pharmaceutical uses, and methods for their snythesis | HONG YUFENG (US) | 2004-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040044037-A1 | Amidino-urea serotonin receptor ligands and compositions, their pharmaceutical uses, and methods for their snythesis | HTR7, HTR1A, HTR2C | KMT2A 4351/4885MEN1 3611/4885MAPT 2819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.