Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 4/20 | 0.42 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 9/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 8/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21996431 | 0.87 | CYP11B2 (0.52) | CYP11B2CYP11B1 | |
| SCHEMBL15657561 | 0.81 | CTSK (0.38) | CYP11B2CYP11B1MCL1 | |
| SCHEMBL3103824 | 0.79 | NOTUM (0.43) | PGRCYP11B2CYP11B1 | |
| SCHEMBL30745584 | 0.79 | NOTUM (0.43) | PGRCYP11B2CYP11B1 | |
| SCHEMBL1816526 | 0.77 | S1PR1 (0.41) | CYP11B2CYP11B1 | |
| SCHEMBL3909066 | 0.77 | AR (0.36) | PGRCYP11B2CYP11B1 | |
| SCHEMBL1810795 | 0.77 | CYP11B2 (0.48) | CYP11B2CYP11B1 | |
| SCHEMBL21996361 | 0.77 | AR (0.54) | PGR | |
| SCHEMBL28686686 | 0.77 | CYP11B1 (0.32) | CYP11B2CYP11B1 | |
| Hydrochloric Acid SCHEMBL16330842 | 0.76 | CYP11B2 (0.47) | CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1610679-A | Efficient process for the preparation of a factor XA inhibitor | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2005-04-27 | — | — | CN | disclosed |
| US-20040198787-A1 | Efficient process for the preparation of a factor Xa inhibitor | LI HUI-YIN (US) | 2004-10-07 | — | — | US | disclosed |
| US-6747158-B2 | ANTICOAGULANTS | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2004-06-08 | — | — | US | disclosed |
| US-6667332-B2 | Benzisoxazolyl-pyrazole derivatives formed by salt formation with maleic acid and hydrochloric acid and cyclization with acetohydroxamic acid | BRISTOL-MYERS SQUIBB COMPANY | 2003-12-23 | — | — | US | disclosed |
| EP-1366045-A2 | EFFICIENT PROCESS FOR THE PREPARATION OF A FACTOR XA INHIBITOR | Bristol-Myers Squibb Pharma Company (US) | 2003-12-03 | — | — | EP | disclosed |
| US-20030212117-A1 | Efficient process for the preparation of a factor Xa inhibitor | LI HUI-YIN (US) | 2003-11-13 | — | — | US | disclosed |
| WO-2002024690-A3 | EFFICIENT PROCESS FOR THE PREPARATION OF A FACTOR XA INHIBITOR | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2003-09-25 | — | — | WO | disclosed |
| WO-2002024690-A8 | EFFICIENT PROCESS FOR THE PREPARATION OF A FACTOR XA INHIBITOR | DU PONT PHARM CO (US) | 2002-08-08 | — | — | WO | disclosed |
| US-20020061917-A1 | Efficient process for the preparation of a factor Xa inhibitor | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2002-05-23 | — | — | US | disclosed |
| WO-2002024690-A2 | EFFICIENT PROCESS FOR THE PREPARATION OF A FACTOR XA INHIBITOR | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2002-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212117-A1 | Efficient process for the preparation of a factor Xa inhibitor | TFPI, F11, F12 | PGR 2589/4885TRPV3 4541/4885CYP11B2 741/4885 |
| US-20040198787-A1 | Efficient process for the preparation of a factor Xa inhibitor | TFPI, F11, F12 | PGR 2589/4885TRPV3 4541/4885CYP11B2 741/4885 |
| US-20020061917-A1 | Efficient process for the preparation of a factor Xa inhibitor | TFPI, F11, F12 | PGR 2589/4885TRPV3 4541/4885CYP11B2 741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.