Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.48 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.48 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.48 |
| ▸ | PHF20 | Q9BVI0 | 1/20 | 0.48 |
| ▸ | MORF4L1 | Q9UBU8 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6699144 | 0.87 | GAA (0.48) | ALDH1A1KMT2AHPGDL3MBTL1L3MBTL3 | |
| SCHEMBL6697423 | 0.85 | NPSR1 (0.49) | ALDH1A1KMT2AHPGDL3MBTL1TSHR | |
| SCHEMBL6701730 | 0.81 | KMT2A (0.48) | ALDH1A1KMT2AHPGDTSHRKDM4E | |
| SCHEMBL6694739 | 0.81 | KMT2A (0.49) | ALDH1A1KMT2AHPGDL3MBTL1TSHR | |
| SCHEMBL6700560 | 0.81 | TP53 (0.60) | ALDH1A1KMT2AHPGDL3MBTL1NAMPT | |
| SCHEMBL6805390 | 0.80 | ALDH1A1 (0.49) | ALDH1A1KMT2AHPGDTSHRGAA | |
| SCHEMBL6698658 | 0.80 | KMT2A (0.50) | ALDH1A1KMT2AHPGDOPRK1TSHR | |
| SCHEMBL6703117 | 0.80 | MAPT (0.47) | ALDH1A1KMT2AHPGDTSHRGAA | |
| SCHEMBL6701774 | 0.78 | KDM4E (0.47) | ALDH1A1KMT2AHPGDTSHRKDM4E | |
| SCHEMBL6698106 | 0.77 | ALDH1A1 (0.46) | ALDH1A1KMT2AHPGDL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040235855-A1 | Phospholipase C inhibitors for use in treating inflammatory disorders | JANSSEN PHARMACEUTICA, N.V. (BE) | 2004-11-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235855-A1 | Phospholipase C inhibitors for use in treating inflammatory disorders | PLA2G4C, PLA2G4B, PLA2G5 | ALDH1A1 1583/4885KMT2A 4455/4885HPGD 1196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.