Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 16/20 | 0.63 |
| ▸ | MMP13 | P45452 | 16/20 | 0.63 |
| ▸ | MMP2 | P08253 | 2/20 | 0.52 |
| ▸ | MMP3 | P08254 | 2/20 | 0.52 |
| ▸ | MMP9 | P14780 | 2/20 | 0.52 |
| ▸ | MMP8 | P22894 | 2/20 | 0.52 |
| ▸ | MMP12 | P39900 | 1/20 | 0.52 |
| ▸ | MMP14 | P50281 | 1/20 | 0.52 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6809628 | 0.98 | MMP1 (0.63) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL6866682 | 0.91 | MMP1 (0.65) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL4614895 | 0.89 | MMP1 (0.51) | MMP1MMP13ARRORCBCL2L1 | |
| SCHEMBL13898698 | 0.88 | MMP1 (0.49) | MMP1MMP13ARFFAR1 | |
| SCHEMBL6872351 | 0.84 | MMP1 (0.67) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL7916340 | 0.84 | MMP1 (0.67) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL5678202 | 0.83 | MMP1 (0.50) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL13898717 | 0.81 | MMP1 (0.61) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL6813130 | 0.81 | MMP1 (0.43) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL6869740 | 0.80 | MMP1 (0.77) | MMP1MMP13MMP2MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0952148-B1 | Cyclobutyl-aryloxyarylsulfonylamino hydroxamic acid derivatives | PFIZER PROD INC (US) | 2004-05-12 | — | — | EP | disclosed |
| US-6156798-A | Cyclobutyl-aryloxyarylsulfonylamino hydroxamic acid derivatives | PFIZER INC (US) | 2000-12-05 | — | — | US | disclosed |
| EP-0952148-A1 | Cyclobutyl-aryloxyarylsulfonylamino hydroxamic acid derivatives | Pfizer Products Inc. (US) | 1999-10-27 | — | — | EP | disclosed |