Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 18/20 | 0.67 |
| ▸ | MMP13 | P45452 | 18/20 | 0.67 |
| ▸ | MMP2 | P08253 | 2/20 | 0.67 |
| ▸ | MMP3 | P08254 | 2/20 | 0.67 |
| ▸ | MMP9 | P14780 | 2/20 | 0.67 |
| ▸ | MMP8 | P22894 | 2/20 | 0.67 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6872351 | 1.00 | MMP1 (0.67) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL7000530 | 0.87 | MMP1 (0.70) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL7000532 | 0.87 | MMP1 (0.70) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL6998188 | 0.87 | MMP1 (0.71) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL6998192 | 0.87 | MMP1 (0.71) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL6809628 | 0.84 | MMP1 (0.63) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL6696963 | 0.84 | MMP1 (0.63) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL7004525 | 0.84 | MMP1 (0.80) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL4048453 | 0.84 | MMP1 (0.80) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL6866682 | 0.84 | MMP1 (0.65) | MMP1MMP13MMP2MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6229025-B1 | MICHAEL ADDITION TO PROPIOLATES | PFIZER INC | 2001-05-08 | — | — | US | disclosed |
| EP-0949244-A2 | Process for preparing hydroxamic acids | Pfizer Products Inc. (US) | 1999-10-13 | — | — | EP | disclosed |