Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 7/20 | 0.49 |
| ▸ | MMP13 | P45452 | 7/20 | 0.49 |
| ▸ | CA1 | P00915 | 5/20 | 0.48 |
| ▸ | CA2 | P00918 | 5/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13898717 | 0.91 | MMP1 (0.61) | MMP1MMP13 | |
| SCHEMBL6809628 | 0.90 | MMP1 (0.63) | MMP1MMP13ARFFAR1 | |
| SCHEMBL6696963 | 0.88 | MMP1 (0.63) | MMP1MMP13ARFFAR1 | |
| SCHEMBL5678202 | 0.87 | MMP1 (0.50) | MMP1MMP13CA1CA2ADAM17 | |
| SCHEMBL5675854 | 0.81 | ALDH1A1 (0.50) | MMP1MMP13LMNA | |
| SCHEMBL4614895 | 0.81 | MMP1 (0.51) | MMP1MMP13AR | |
| SCHEMBL6866682 | 0.81 | MMP1 (0.65) | MMP1MMP13 | |
| SCHEMBL14507736 | 0.80 | LMNA (0.47) | CA1CA2LMNA | |
| SCHEMBL7066448 | 0.76 | MMP13 (0.62) | MMP1MMP13 | |
| SCHEMBL4615932 | 0.75 | LMNA (0.49) | CA1CA2LMNACYP2C9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504537-B2 | Hydroxamic acid derivative and MMP inhibitor containing the same as active ingredient | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-03-17 | — | — | US | disclosed |