Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4307542 | 0.96 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1KDM4ERAB9ALMNA | |
| SCHEMBL4306015 | 0.85 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1KDM4ERAB9AHPGD | |
| SCHEMBL4310711 | 0.85 | KMT2A (0.46) | SMN1; SMN2ALDH1A1KDM4ERAB9AHPGD | |
| SCHEMBL4309398 | 0.85 | HSD17B10 (0.48) | SMN1; SMN2ALDH1A1KDM4ERAB9AF10 | |
| SCHEMBL13950057 | 0.83 | ALDH1A1 (0.48) | SMN1; SMN2ALDH1A1KDM4ERAB9ALMNA | |
| SCHEMBL13950080 | 0.83 | KMT2A (0.46) | SMN1; SMN2ALDH1A1KDM4ELMNAF10 | |
| SCHEMBL4302257 | 0.82 | SMN1; SMN2 (0.74) | SMN1; SMN2ALDH1A1KDM4ERAB9ALMNA | |
| SCHEMBL6697366 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1KDM4ERAB9ALMNA | |
| SCHEMBL4314316 | 0.80 | ACHE (0.45) | SMN1; SMN2ALDH1A1KDM4ERAB9AHPGD | |
| SCHEMBL13950089 | 0.77 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1HPGDF10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1414817-A1 | SUBSTITUTED ISOINDOLES AND E USE THEREOF | Bayer HealthCare AG (DE) | 2004-05-06 | — | — | EP | disclosed |
| WO-2003011858-A1 | SUBSTITUTED ISOINDOLES AND E USE THEREOF | BAYER HEALTHCARE AG (DE) | 2003-02-13 | — | — | WO | disclosed |