SCHEMBL6697430

SCHEMBL6697430

Cc1nc(-c2cccc(Cl)c2Cl)[nH]c1-c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 2/20 0.47
GAA P10253 1/20 0.47
SI P14410 1/20 0.47
MGAM2 Q2M2H8 1/20 0.47
CXCR2 P25025 1/20 0.45
MAPK14 Q16539 3/20 0.44
MAPK13 O15264 1/20 0.44
RAF1 P04049 1/20 0.44
MAPK12 P53778 1/20 0.44
MAPK11 Q15759 1/20 0.44
NUDT1 P36639 2/20 0.42
KDM4E B2RXH2 3/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
ALDH1A1 P00352 1/20 0.42
GPR55 Q9Y2T6 1/20 0.42
CYP1A2 P05177 2/20 0.41
CYP3A4 P08684 2/20 0.41
CYP2D6 P10635 2/20 0.41
CYP2C9 P11712 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10719284 0.84 MGAM (0.61) MGAMMAPK14MAPK13RAF1MAPK12
SCHEMBL3128349 0.79 NPY5R (0.48) MGAMGAASIMGAM2CXCR2
SCHEMBL31305568 0.79 NPY5R (0.48) MGAMGAASIMGAM2CXCR2
SCHEMBL6466301 0.78 MAPK14 (0.70) MGAMMAPK14MAPK13RAF1MAPK12
SCHEMBL11516210 0.77 MAPK13 (0.53) GAAMAPK14MAPK13RAF1MAPK12
SCHEMBL7369697 0.76 NPY5R (0.54) MGAMGAASIMGAM2MAPK14
SCHEMBL20425689 0.76 GAA (0.58) MGAMGAASIMGAM2CXCR2
SCHEMBL20425291 0.75 MAPK13 (0.60) MGAMGAASIMGAM2MAPK14
Hydrochloric Acid SCHEMBL23736197 0.75 GAA (0.57) MGAMGAASIMGAM2CXCR2
SCHEMBL8313104 0.74 MEN1 (0.47) MGAMGAAMAPK14MAPK13RAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2004277386-A 2-(DICHLOROPHENYL)-4-METHYL-5-PHENYLIMIDAZOLE COMPOUND SHIKOKU CHEM CORP 2004-10-07 JP disclosed