Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 5/20 | 0.54 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.52 |
| ▸ | PTGES | O14684 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.47 |
| ▸ | RAF1 | P04049 | 1/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370892 | 0.86 | NPY5R (0.57) | NPY5RCYP11B1CYP11B2CYP3A4CYP2C9 | |
| SCHEMBL7367787 | 0.86 | ROS1 (0.48) | NPY5RCYP11B1CYP11B2PTGESCYP3A4 | |
| SCHEMBL7376655 | 0.84 | MGAM (0.52) | NPY5RCYP11B1CYP11B2SMN1; SMN2TP53 | |
| SCHEMBL7370832 | 0.84 | CYP11B1 (0.52) | NPY5RCYP11B1CYP11B2SMN1; SMN2NPC1 | |
| SCHEMBL7369715 | 0.84 | CYP11B1 (0.52) | NPY5RCYP11B1CYP11B2SMN1; SMN2MAPK14 | |
| SCHEMBL13115247 | 0.83 | NPY5R (0.51) | NPY5RCYP11B1CYP11B2PTGESCYP3A4 | |
| SCHEMBL7372656 | 0.82 | ALOX5 (0.50) | NPY5RCYP11B1CYP11B2SMN1; SMN2NPC1 | |
| SCHEMBL27692933 | 0.82 | CYP11B1 (0.50) | NPY5RCYP11B1CYP11B2SMN1; SMN2NPC1 | |
| SCHEMBL7367947 | 0.81 | NPY5R (0.63) | NPY5RCYP11B1CYP11B2SMN1; SMN2MAPK13 | |
| Hydrochloric Acid SCHEMBL7369410 | 0.81 | PDE5A (0.58) | NPY5RCYP11B1CYP11B2SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799052-B1 | NEW ANTITHROMBOTIC FORMULATION, PROCESS FOR ITS MANUFACTURING, AND USE THEREOF | ASTRAZENECA AB (SE) | 2001-11-14 | — | — | EP | disclosed |
| EP-0701568-B1 | NEW PEPTIDE DERIVATIVES | ASTRAZENECA AB (SE) | 2001-04-25 | — | — | EP | disclosed |
| EP-1067136-A1 | New peptide derivatives | AstraZeneca AB (SE) | 2001-01-10 | — | — | EP | disclosed |
| US-5939392-A | THROMBIN INHIBITORS, ANTICOAGULANTS AND ANTIINFLAMMATORY AGENTS | ASTRA AKTIEBOLAG (SE) | 1999-08-17 | — | — | US | disclosed |
| US-5856307-A | Peptide derivatives as kininogenase inhibitors | ASTRA AKTIEBOLAG (SE) | 1999-01-05 | — | — | US | disclosed |
| US-5795896-A | Antithrombotic formulation, process for its manufacturing, and use thereof | ASTRA AKTIEBOLAG (SE) | 1998-08-18 | — | — | US | disclosed |
| US-5783563-A | Method for treatment or prophylaxis of venous thrombosis | ASTRA AKTIEBOLAG | 1998-07-21 | — | — | US | disclosed |
| US-5780631-A | ANTICOAGLUANT | ASTRA AKTIEBOLAG (SE) | 1998-07-14 | — | — | US | disclosed |
| US-5723444-A | ENZYME INHIBITORS AND ANTICOAGULANTS | ASTRA AB (SE) | 1998-03-03 | — | — | US | disclosed |
| EP-0799052-A1 | NEW ANTITHROMBOTIC FORMULATION, PROCESS FOR ITS MANUFACTURING, AND USE THEREOF | Astra Aktiebolag (SE) | 1997-10-08 | — | — | EP | disclosed |
| US-5602253-A | STARTING MATERIAL FOR SERINE PROTEASE INHIBITORS | AKTIEBOLAGET ASTRA (SE) | 1997-02-11 | — | — | US | disclosed |
| WO-1996016671-A1 | NEW ANTITHROMBOTIC FORMULATION, PROCESS FOR ITS MANUFACTURING, AND USE THEREOF | ASTRA AKTIEBOLAG (SE) | 1996-06-06 | — | — | WO | disclosed |
| EP-0701568-A1 | NEW PEPTIDE DERIVATIVES | Astra Aktiebolag (SE) | 1996-03-20 | — | — | EP | disclosed |
| WO-1994029336-A1 | NEW PEPTIDE DERIVATIVES | ASTRA AKTIEBOLAG (SE) | 1994-12-22 | — | — | WO | disclosed |
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| CN-87105680-A | Imidazolium compounds and preparation method thereof and comprise the pharmaceutical composition of this compound | — | 1988-04-27 | — | — | CN | disclosed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |