SCHEMBL6697449

SCHEMBL6697449

CC(C)(O)C(=O)c1ccc(Sc2ccc(C(=O)C(C)(C)O)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
LMNA P02545 2/20 0.56
ALDH1A1 P00352 3/20 0.48
MAPK1 P28482 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
TSHR P16473 1/20 0.40
CA2 P00918 1/20 0.38
NR1H2 P55055 1/20 0.37
MEN1 O00255 3/20 0.37
MAPT P10636 3/20 0.37
KMT2A Q03164 3/20 0.37
HTT P42858 2/20 0.37
RARB P10826 1/20 0.37
RARG P13631 1/20 0.37
RXRA P19793 1/20 0.37
RXRB P28702 1/20 0.37
RXRG P48443 1/20 0.37
MLYCD O95822 2/20 0.36
PLK1 P53350 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10384605 0.92 HPGD (0.61) HPGDL3MBTL1LMNAALDH1A1MAPK1
SCHEMBL29206743 0.88 ALDH1A1 (0.51) HPGDL3MBTL1LMNAALDH1A1MEN1
SCHEMBL29206742 0.86 ABCC9 (0.46) HPGDL3MBTL1LMNAALDH1A1MAPK1
SCHEMBL11298330 0.86 CA2 (0.46) LMNAALDH1A1SMN1; SMN2TSHRCA2
SCHEMBL6964815 0.85 ALDH1A1 (0.54) HPGDL3MBTL1LMNAALDH1A1MAPK1
SCHEMBL10871719 0.84 HPGD (0.58) HPGDL3MBTL1LMNAALDH1A1MAPK1
SCHEMBL8630154 0.83 HPGD (0.56) HPGDL3MBTL1LMNAALDH1A1MAPK1
SCHEMBL10941151 0.80 ALDH1A1 (0.50) HPGDLMNAALDH1A1MAPK1SMN1; SMN2
SCHEMBL1553588 0.80 ALDH1A1 (0.72) HPGDL3MBTL1LMNAALDH1A1MAPK1
SCHEMBL1555398 0.80 HPGD (0.38) HPGDL3MBTL1LMNAALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110563589-A Mono-or di-methyl cinnamate photoinitiator, and preparation method and application thereof 湖北固润科技股份有限公司 2019-12-13 CN disclosed
EP-1435934-A1 5'-ACYLAMINO-1,1'-BIPHENYL-4-CARBOXAMIDE DERIVATIVES AND THEIR USE AS P38 KINASE INHIBITORS GLAXO GROUP LIMITED (GB) 2004-07-14 EP disclosed
WO-2003032971-A1 5’-ACYLAMINO-1,1’-BIPHENYL-4-CARBOXAMIDE DERIVATIVES AND THEIR USE AS P38 KINASE INHIBITORS GLAXO GROUP LIMITED (GB) 2003-04-24 WO disclosed
US-4318791-A PHOTOPOLYMERIZABLE SYSTEM FOR INKS CIBA-GEIGY CORPORATION (US) 1982-03-09 US disclosed
US-4315807-A Sensitizers for photopolymerization CIBA-GEIGY CORPORATION (US) 1982-02-16 US disclosed