Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.67 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.67 |
| ▸ | ADORA2A | P29274 | 10/20 | 0.62 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.62 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.56 |
| ▸ | GRK6 | P43250 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17279794 | 0.85 | NR1H2 (0.86) | NR1H2NR1H3ADORA2AADORA1DCUN1D1 | |
| SCHEMBL29035880 | 0.84 | NR1H2 (0.89) | NR1H2NR1H3ADORA2AADORA1DCUN1D1 | |
| SCHEMBL30149870 | 0.84 | NR1H2 (0.89) | NR1H2NR1H3ADORA2AADORA1DCUN1D1 | |
| SCHEMBL12302837 | 0.77 | ACHE (0.54) | ACHENOTUMDYRK1ACLK4NPC1 | |
| SCHEMBL27852106 | 0.77 | NR1H2 (0.71) | NR1H2NR1H3ADORA2AADORA1DCUN1D1 | |
| SCHEMBL17279684 | 0.76 | NR1H2 (0.67) | NR1H2NR1H3ADORA2AADORA1DCUN1D1 | |
| SCHEMBL15117074 | 0.76 | NR1H2 (0.80) | NR1H2NR1H3ADORA2AADORA1DCUN1D1 | |
| SCHEMBL17279722 | 0.76 | NR1H2 (0.68) | NR1H2NR1H3ADORA2ANPC1TP53 | |
| SCHEMBL12172015 | 0.76 | NR1H2 (0.74) | NR1H2NR1H3ADORA2AADORA1DCUN1D1 | |
| SCHEMBL6451523 | 0.75 | NR1H2 (0.65) | NR1H2NR1H3ADORA2AADORA1DCUN1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040248950-A1 | Apo ai expression accelerating agent | SHIONOGI & CO., LTD. (JP) | 2004-12-09 | — | — | US | disclosed |
| EP-1419770-A1 | APO AI EXPRESSION ACCELERATING AGENT | SHIONOGI & CO., LTD. (JP) | 2004-05-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248950-A1 | Apo ai expression accelerating agent | APOB, APOL1, NR1H2 | NR1H2 3/4885NR1H3 4/4885ADORA2A 357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.