Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.32 |
| ▸ | ALPG | P10696 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19374385 | 0.75 | — | — | |
| SCHEMBL25330814 | 0.75 | — | — | |
| SCHEMBL4478797 | 0.72 | CYP19A1 (0.46) | — | |
| SCHEMBL5828068 | 0.69 | MEN1 (0.43) | ALDH1A1MEN1KMT2AHMOX1ALPG | |
| Bromide SCHEMBL2235882 | 0.69 | — | — | |
| SCHEMBL3773335 | 0.68 | TSHR (0.51) | — | |
| SCHEMBL21111119 | 0.65 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2AHMOX1ALPG | |
| SCHEMBL21111121 | 0.65 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2AHMOX1ALPG | |
| SCHEMBL21111097 | 0.64 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL27603968 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100338059-C | 3-(4-amidopyrrol-2-2ylmethlidene)-2-indolinone derivatives as protein kinase inhibitors | SUGEN CO LTD (US) | 2007-09-19 | — | — | CN | disclosed |
| US-20040186160-A1 | Hexahydro-cyclohepta-pyrrole oxindole as potent kinase inhibitors | SUGEN, INC. | 2004-09-23 | — | — | US | disclosed |
| CN-1529704-A | 3-(4-amidopyrrol-2-2ylmethlidene)-2-indolinone derivatives as protein kinase inhibitors | �ո��� | 2004-09-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040186160-A1 | Hexahydro-cyclohepta-pyrrole oxindole as potent kinase inhibitors | MAP3K15, MAP3K20, MAP3K19 | ALDH1A1 3282/4885MEN1 4639/4885KMT2A 1217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.