SCHEMBL5828068

SCHEMBL5828068

N[C@@H](Cn1cnnn1)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.43
ALDH1A1 P00352 1/20 0.43
KMT2A Q03164 1/20 0.43
SLC1A3 P43003 1/20 0.40
HMOX1 P09601 1/20 0.40
TP53 P04637 1/20 0.39
GRIA1 P42261 4/20 0.37
GRIA2 P42262 4/20 0.37
GRIA4 P48058 4/20 0.37
GRIK5 Q16478 1/20 0.37
GRIA3 P42263 3/20 0.37
STAT5B P51692 1/20 0.37
ALPG P10696 1/20 0.36
TYR P14679 1/20 0.35
DOHH Q9BU89 1/20 0.35
KDM4E B2RXH2 1/20 0.35
DPP4 P27487 1/20 0.34
PTGS1 P23219 1/20 0.34
SLC7A11 Q9UPY5 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25660498 0.82 ALDH1A1 (0.50) MEN1ALDH1A1KMT2ASLC1A3HMOX1
SCHEMBL2363480 0.80 ALDH1A1 (0.47) MEN1ALDH1A1KMT2ASLC1A3HMOX1
SCHEMBL6395050 0.74 FOLH1 (0.55) SLC1A3TYRDOHHKDM4E
SCHEMBL612982 0.74 FOLH1 (0.55) SLC1A3TYRDOHHKDM4E
SCHEMBL503194 0.70 EGLN3 (0.50) MEN1ALDH1A1KMT2AGRIA1GRIA2
SCHEMBL503649 0.70 FDPS (0.51) ALDH1A1GRIA1GRIA2GRIA4GRIK5
SCHEMBL941137 0.70 EGLN3 (0.50) MEN1ALDH1A1KMT2AGRIA1GRIA2
SCHEMBL4153679 0.70 FDPS (0.51) ALDH1A1GRIA1GRIA2GRIA4GRIK5
SCHEMBL9462503 0.70 FDPS (0.51) ALDH1A1GRIA1GRIA2GRIA4GRIK5
SCHEMBL14489820 0.70 EGLN3 (0.50) MEN1ALDH1A1KMT2AGRIA1GRIA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6939967-B2 Non-proteinogenic L-amino acids Consortium für elektrochemische Industrie GmbH (DE) 2005-09-06 US claimed
US-20040197879-A1 Process for producing non-proteinogenic L-amino acids by fermentation CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH 2004-10-07 US claimed
EP-1191106-B1 Process for the fermentative preparation of non-proteinogenic L-amino acids CONSORTIUM ELEKTROCHEM IND (DE) 2004-04-28 EP claimed
US-20020039767-A1 Process for producing non-proteinogenic L-amino acids by fermentation CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH 2002-04-04 US claimed
CN-119236050-A Modulation of complement activity RA制药公司 2025-01-03 CN disclosed
US-7015331-B2 Non-proteinogenic L-amino acids Consortium für elektrochemische Industrie GmbH (DE) 2006-03-21 US disclosed
US-20050222426-A1 Non-proteinogenic L-amino acids CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH 2005-10-06 US disclosed
US-6939967-B2 Non-proteinogenic L-amino acids Consortium für elektrochemische Industrie GmbH (DE) 2005-09-06 US disclosed
US-20040197879-A1 Process for producing non-proteinogenic L-amino acids by fermentation CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH 2004-10-07 US disclosed
US-6756216-B2 BATCH PROCESSING USING NUCLEOPHILIC COMPOUND Consortium für elektrochemische Industrie GmbH (DE) 2004-06-29 US disclosed
US-20020039767-A1 Process for producing non-proteinogenic L-amino acids by fermentation CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH 2002-04-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050222426-A1 Non-proteinogenic L-amino acids BCAT2, BCAT1, CBS MEN1 3039/4885ALDH1A1 1606/4885KMT2A 2140/4885
US-20020039767-A1 Process for producing non-proteinogenic L-amino acids by fermentation CBS, BCAT2, BCAT1 MEN1 3402/4885ALDH1A1 2149/4885KMT2A 2412/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.