SCHEMBL6697614

SCHEMBL6697614

CCON=C(C(C)=NOCc1ccccc1N(C)C(=O)OC)c1ccc(Oc2ccc(C(F)(F)F)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
LIPE Q05469 4/20 0.37
MAPK14 Q16539 2/20 0.37
MAOB P27338 2/20 0.33
MMP2 P08253 2/20 0.33
MMP9 P14780 2/20 0.33
MAOA P21397 1/20 0.32
PPARG P37231 2/20 0.32
PPARA Q07869 2/20 0.32
BACE1 P56817 1/20 0.32
LTA4H P09960 1/20 0.32
EPHX2 P34913 1/20 0.32
S1PR1 P21453 1/20 0.32
PTGS2 P35354 1/20 0.32
ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7466202 0.88 MEN1 (0.37) MEN1KMT2ALIPEMAPK14MAOB
SCHEMBL6695269 0.83 MEN1 (0.38) MEN1KMT2ALIPEMAPK14MAOB
SCHEMBL6695270 0.83 MEN1 (0.38) MEN1KMT2ALIPEMAPK14MAOB
SCHEMBL7545346 0.81 MAPK14 (0.37) MEN1KMT2ALIPEMAPK14MAOB
SCHEMBL7467425 0.81 MAOB (0.42) MAOBMAOAPPARG
SCHEMBL7492706 0.80 HIF1A (0.42) MEN1KMT2AMAPK14MAOBMAOA
SCHEMBL6697613 0.80 MEN1 (0.38) MEN1KMT2ALIPEMAPK14MMP2
SCHEMBL7470567 0.79 HIF1A (0.38) MEN1KMT2AMAPK14MAOBS1PR1
SCHEMBL7470560 0.79 HIF1A (0.38) MEN1KMT2AMAPK14MAOBS1PR1
SCHEMBL6695416 0.78 PTGS2 (0.34) PPARGPPARAS1PR1PTGS2ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040023806-A1 N-phenylcarbamates having a microbicide insecticide and acaricide effect BAYER AKTIENGESELLSCHAFT (DE) 2004-02-05 US claimed
US-20040023806-A1 N-phenylcarbamates having a microbicide insecticide and acaricide effect BAYER AKTIENGESELLSCHAFT (DE) 2004-02-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040023806-A1 N-phenylcarbamates having a microbicide insecticide and acaricide effect CBR3, CBR1, CYP1B1 MEN1 3045/4885KMT2A 3292/4885LIPE 741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.