SCHEMBL6697613

SCHEMBL6697613

CCO/N=C(C(/C)=C(\ON)c1ccccc1N(C)C(=O)OC)\c1ccc(Oc2ccc(C(F)(F)F)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
LIPE Q05469 4/20 0.36
MAPK14 Q16539 2/20 0.36
BACE1 P56817 2/20 0.33
CYP11B1 P15538 1/20 0.33
CYP11B2 P19099 1/20 0.33
LTA4H P09960 1/20 0.31
EPHX2 P34913 1/20 0.31
SCN9A Q15858 2/20 0.31
MMP2 P08253 2/20 0.31
MMP9 P14780 2/20 0.31
PPARG P37231 1/20 0.31
PPARA Q07869 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7466206 0.82 MAPK14 (0.36) MEN1KMT2AMAPK14BACE1LTA4H
SCHEMBL7470568 0.81 MAPK14 (0.38) MEN1KMT2AMAPK14BACE1CYP11B1
SCHEMBL6697614 0.80 MEN1 (0.39) MEN1KMT2ALIPEMAPK14BACE1
SCHEMBL6695270 0.78 MEN1 (0.38) MEN1KMT2ALIPEMAPK14BACE1
SCHEMBL6695269 0.78 MEN1 (0.38) MEN1KMT2ALIPEMAPK14BACE1
SCHEMBL6695411 0.77 RAB9A (0.35) MEN1KMT2ALMNA
SCHEMBL6692299 0.76 MEN1 (0.37) MEN1KMT2ALIPEMAPK14CYP11B1
SCHEMBL6692302 0.76 MEN1 (0.37) MEN1KMT2ALIPEMAPK14CYP11B1
SCHEMBL8544631 0.76 MAPK14 (0.37) MAPK14LTA4H
SCHEMBL7467262 0.75 MAPK14 (0.39) KMT2AMAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040023806-A1 N-phenylcarbamates having a microbicide insecticide and acaricide effect BAYER AKTIENGESELLSCHAFT (DE) 2004-02-05 US claimed
US-20040023806-A1 N-phenylcarbamates having a microbicide insecticide and acaricide effect BAYER AKTIENGESELLSCHAFT (DE) 2004-02-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040023806-A1 N-phenylcarbamates having a microbicide insecticide and acaricide effect CBR3, CBR1, CYP1B1 MEN1 3045/4885KMT2A 3292/4885LIPE 741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.