SCHEMBL669768

SCHEMBL669768

CC1CC(C)(C)CC1(c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 11/20 0.57
ESR1 P03372 8/20 0.57
MMP2 P08253 1/20 0.34
MMP9 P14780 1/20 0.34
CNR2 P34972 2/20 0.30
CYP3A4 P08684 1/20 0.30
AR P10275 1/20 0.30
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
HTR6 P50406 1/20 0.30
ESRRG P62508 1/20 0.30
SLC6A3 Q01959 1/20 0.30
HSD17B10 Q99714 1/20 0.30
NPY1R P25929 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14451248 0.84 ESR1 (0.43) ESR2ESR1
SCHEMBL8776956 0.82 ESR2 (0.46) ESR2ESR1MMP2MMP9
SCHEMBL1415063 0.81 MAOB (0.39) CYP3A4ARTSHR
SCHEMBL17532655 0.78 ESR1 (0.46) ESR2ESR1AR
SCHEMBL1415062 0.78 ESR1 (0.34) ESR2ESR1
SCHEMBL2777308 0.77 ESR1 (0.39) ESR2ESR1TSHRHTR6
SCHEMBL2780565 0.75 ACHE (0.41) ESR2ESR1
SCHEMBL15135604 0.73 ESR2 (0.51) ESR2ESR1MMP2MMP9
SCHEMBL21291805 0.73 ESR2 (1.00) ESR2ESR1MMP2MMP9CYP3A4
SCHEMBL18187 0.73 ESR2 (1.00) ESR2ESR1MMP2MMP9CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 444 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2346954-B1 PREPARATION FOR PRODUCING A COVER LAYER FOR AN ELECTROLUMINESCENT SECURITY ELEMENT OF A SECURITY DOCUMENT AND/OR VALUE DOCUMENT BUNDESDRUCKEREI GMBH (DE) 2017-04-12 EP claimed
EP-2676803-B1 Method for producing a polymer layer composite with multilayer personalization and/or individualisation BUNDESDRUCKEREI GMBH (DE) 2016-09-14 EP claimed
US-20160129679-A1 METHOD FOR THE PRODUCTION OF A POLYCARBONATE LAMINATE BUNDESDRUCKEREI GMBH (DE) 2016-05-12 US claimed
US-8636862-B2 Method for producing a polycarbonate layered composite BUNDESDRUCKEREI GMBH (DE) 2014-01-28 US claimed
EP-2676803-A1 Method for producing a polymer layer composite with multilayer personalization and/or individualisation Bundesdruckerei GmbH (DE) 2013-12-25 EP claimed
EP-2205436-B1 METHOD FOR PRODUCING A POLYCARBONATE LAYERED COMPOSITE BUNDESDRUCKEREI GMBH (DE) 2011-04-20 EP claimed
EP-2205437-B1 METHOD FOR PRODUCING A POLYCARBONATE LAYERED COMPOSITE BUNDESDRUCKEREI GMBH (DE) 2011-04-13 EP claimed
EP-2205686-B1 METHOD FOR THE PRODUCTION OF A POLYCARBONATE LAMINATE BUNDESDRUCKEREI GMBH (DE) 2011-03-16 EP claimed
US-20100310812-A1 METHOD FOR PRODUCING A POLYCARBONATE LAYERED COMPOSITE BUNDESDRUCKEREI GMBH (DE) 2010-12-09 US claimed
EP-1660556-B1 COPOLYETHERIMIDES SABIC INNOVATIVE PLASTICS IP (NL) 2009-05-13 EP claimed
US-7115785-B2 Method for making salts hydroxy-substituted hydrocarbons GENERAL ELECTRIC COMPANY (US) 2006-10-03 US claimed
EP-1660556-A1 COPOLYETHERIMIDES GENERAL ELECTRIC COMPANY (US) 2006-05-31 EP claimed
EP-1660422-A2 METHOD FOR MAKING SALTS OF HYDROXY-SUBSTITUTED HYDROCARBONS GENERAL ELECTRIC COMPANY (US) 2006-05-31 EP claimed
WO-2005023901-A1 COPOLYETHERIMIDES GENERAL ELECTRIC COMPANY (US) 2005-03-17 WO claimed
WO-2005021477-A2 METHOD FOR MAKING SALTS OF HYDROXY-SUBSTITUTED HYDROCARBONS GENERAL ELECTRIC COMPANY (US) 2005-03-10 WO claimed
US-20050049439-A1 Method for making salts hydroxy-substituted hydrocarbons GENERAL ELECTRIC COMPANY 2005-03-03 US claimed
US-6849706-B1 Copolyetherimides GENERAL ELECTRIC COMPANY (US) 2005-02-01 US claimed
US-6706788-B2 HEAT RESISTANCE, WELD LINE STRENGTH BAYER AKTIENGESELLSCHAFT (DE) 2004-03-16 US claimed
US-6337371-B2 MIXTURE TECHNO POLYMER CO., LTD. (JP) 2002-01-08 US claimed
US-6262173-B1 HAVING IMPACT RESISTANCE, HEAT RESISTANCE, CHEMICAL RESISTANCE AND WEATHER RESISTANCE TECHNO POLYMER CO., LTD. (JP) 2001-07-17 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050049439-A1 Method for making salts hydroxy-substituted hydrocarbons HDHD5, SHH, HAAO ESR2 3768/4885ESR1 2614/4885MMP2 518/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.