Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 12/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 3/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 2/20 | 1.00 |
| ▸ | THPO | P40225 | 1/20 | 1.00 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.72 |
| ▸ | SCN1A | P35498 | 2/20 | 0.72 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.72 |
| ▸ | TSHR | P16473 | 2/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.72 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.72 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.72 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.72 |
| ▸ | GBA1 | P04062 | 1/20 | 0.72 |
| ▸ | MAOA | P21397 | 1/20 | 0.72 |
| ▸ | HTR2A | P28223 | 1/20 | 0.72 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.72 |
| ▸ | HTR2B | P41595 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6271316 | 1.00 | SCN4A (1.00) | SCN4ACYP2D6CYP1A2CYP3A4NFKB1 | |
| SCHEMBL6275226 | 1.00 | SCN4A (1.00) | SCN4ACYP2D6CYP1A2CYP3A4NFKB1 | |
| Hydrochloric Acid SCHEMBL11709046 | 0.98 | SCN4A (0.96) | SCN4ACYP2D6CYP1A2CYP3A4NFKB1 | |
| Mexiletine SCHEMBL16081 | 0.84 | SCN4A (1.00) | SCN4ACYP2D6CYP1A2CYP3A4NFKB1 | |
| (S)-Mexiletine SCHEMBL13046569 | 0.84 | SCN4A (1.00) | SCN4ACYP2D6CYP1A2CYP3A4NFKB1 | |
| (R)-Mexiletine SCHEMBL16082 | 0.84 | SCN4A (1.00) | SCN4ACYP2D6CYP1A2CYP3A4NFKB1 | |
| Mexiletine SCHEMBL8858385 | 0.84 | SCN4A (1.00) | SCN4ACYP2D6CYP1A2CYP3A4NFKB1 | |
| Mexiletine SCHEMBL6521444 | 0.82 | SCN5A (1.00) | SCN4ACYP2D6CYP1A2CYP3A4NFKB1 | |
| (R)-Mexiletine SCHEMBL29366590 | 0.82 | SCN5A (1.00) | SCN4ACYP2D6CYP1A2CYP3A4NFKB1 | |
| Mexiletine SCHEMBL6665250 | 0.82 | SCN5A (1.00) | SCN4ACYP2D6CYP1A2CYP3A4NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116535-A1 | Use | ISOMEX LIMITED (GB) | 2004-06-17 | — | — | US | disclosed |