SCHEMBL6271316

SCHEMBL6271316

Cc1cccc(C)c1OCC(N)C(C)C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SCN4A P35499 12/20 1.00
▸ CYP2D6 P10635 3/20 1.00
▸ CYP1A2 P05177 2/20 1.00
▸ CYP3A4 P08684 2/20 1.00
▸ NFKB1 P19838 2/20 1.00
▸ THPO P40225 1/20 1.00
▸ SCN5A Q14524 3/20 0.72
▸ LMNA P02545 3/20 0.72
▸ SCN1A P35498 2/20 0.72
▸ SCN9A Q15858 2/20 0.72
▸ TSHR P16473 2/20 0.72
▸ CYP2C9 P11712 1/20 0.72
▸ KCNK3 O14649 1/20 0.72
▸ CACNA1F O60840 1/20 0.72
▸ KCNK2 O95069 1/20 0.72
▸ GBA1 P04062 1/20 0.72
▸ MAOA P21397 1/20 0.72
▸ HTR2A P28223 1/20 0.72
▸ SLC6A4 P31645 1/20 0.72
▸ HTR2B P41595 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6275226 1.00 SCN4A (1.00) SCN4ACYP2D6CYP1A2CYP3A4NFKB1
SCHEMBL6697801 1.00 SCN4A (1.00) SCN4ACYP2D6CYP1A2CYP3A4NFKB1
Hydrochloric Acid SCHEMBL11709046 0.98 SCN4A (0.96) SCN4ACYP2D6CYP1A2CYP3A4NFKB1
(S)-Mexiletine SCHEMBL13046569 0.84 SCN4A (1.00) SCN4ACYP2D6CYP1A2CYP3A4NFKB1
Mexiletine SCHEMBL8858385 0.84 SCN4A (1.00) SCN4ACYP2D6CYP1A2CYP3A4NFKB1
(R)-Mexiletine SCHEMBL16082 0.84 SCN4A (1.00) SCN4ACYP2D6CYP1A2CYP3A4NFKB1
Mexiletine SCHEMBL16081 0.84 SCN4A (1.00) SCN4ACYP2D6CYP1A2CYP3A4NFKB1
Mexiletine SCHEMBL42226 0.82 SCN5A (1.00) SCN4ACYP2D6CYP1A2CYP3A4NFKB1
(S)-Mexiletine SCHEMBL3645798 0.82 SCN5A (1.00) SCN4ACYP2D6CYP1A2CYP3A4NFKB1
(R)-Mexiletine SCHEMBL29366590 0.82 SCN5A (1.00) SCN4ACYP2D6CYP1A2CYP3A4NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260125375-A1 SUBSTITUTED 1H-PYRAZOLO-PYRIDINE AND -PYRIMIDINE COMPOUNDS PFIZER INC. (US) 2026-05-07 — — US disclosed
EP-4737442-A1 DIAMINOVINYLIDENE DERIVATIVE OR SALT THEREOF, PEST CONTROL AGENT CONTAINING SAID COMPOUND, AND METHODS FOR USING THESE ADEKA CORPORATION (JP) 2026-05-06 — — EP disclosed
US-12585187-B2 Actinic ray-sensitive or radiation-sensitive resin composition, resist film, pattern forming method, method for manufacturing electronic device, and compound FUJIFILM CORPORATION (JP) 2026-03-24 — — US disclosed
US-20260062435-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF WAVE LIFE SCIENCES LTD (SG) 2026-03-05 — — US disclosed
US-12564656-B2 Sprayable tissue adhesive with biodegradation for wound treatment UNIVERSITY OF MARYLAND COLLEGE PARK (US) 2026-03-03 — — US disclosed
EP-4694824-A1 WASTE CONTAINER COMPRISING PERMANENT CLOSING MEANS ARRANGED WITH DEPTH-CONTROLLING ELEMENTS AND METHOD FOR USING THE SAME FrostPharma AB (SE) 2026-02-18 — — EP disclosed
US-12554196-B2 Actinic ray-sensitive or radiation-sensitive resin composition, pattern forming method, resist film, method for manufacturing electronic device, compound, and method for producing compound FUJIFILM CORPORATION (JP) 2026-02-17 — — US disclosed
EP-4673453-A1 DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS FOR RNA INTERFERENCE AND METHODS RELATING THERETO Wave Life Sciences Ltd. (SG) 2026-01-07 — — EP disclosed
US-12481215-B2 Active-light-sensitive or radiation-sensitive resin composition, resist film, pattern formation method, method for manufacturing electronic device, compound, and resin FUJIFILM CORPORATION (JP) 2025-11-25 — — US disclosed
EP-3898858-B1 USE OF ORGANOSILOXANES WITH AROMATIC REMNANTS IN RELEASE COATINGS EVONIK OPERATIONS GMBH (DE) 2025-11-19 — — EP disclosed
US-20220071211-A1 SUBSTITUTED PYRIDINYLOXYBENZENES AND SALTS THEREOF AND USE THEREOF AS HERBICIDAL AGENTS BAYER AKTIENGESELLSCHAFT (DE) 2022-03-10 — — US disclosed
EP-3949731-A1 PYRIDAZINONE COMPOUND AND HERBICIDE Nissan Chemical Corporation (JP) 2022-02-09 — — EP disclosed
CN-100379411-C Use of compound for treating tinnitus ISOMEX LTD (GB) 2008-04-09 — — CN disclosed
EP-1365757-B1 Use of xylyloxy alkyl amines for treating tinnitus ISOMEX LTD (GB) 2005-12-28 — — EP disclosed
US-20040116535-A1 Use ISOMEX LIMITED (GB) 2004-06-17 — — US disclosed
CN-1491107-A Use of compound for treating tinnitus — 2004-04-21 — — CN disclosed
EP-1365757-A1 NEW USE Isomex Limited (GB) 2003-12-03 — — EP disclosed
WO-2002062328-A1 NEW USE ISOMEX LIMITED (GB) 2002-08-15 — — WO disclosed
US-4031244-A ANTICONVULSIVES, ANTIARRHYTHMIA BOEHRINGER INGELHEIM GMBH (DT) 1977-06-21 — — US disclosed
US-3954872-A 1-(2',6'-Dimethyl-phenoxy)-2-amino-alkanes and salts thereof BOEHRINGER INGELHEIM GMBH (DT) 1976-05-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062435-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF NSUN3, METTL3, RNASE1 SCN4A 2446/4885CYP2D6 3558/4885CYP1A2 4689/4885
US-12564656-B2 Sprayable tissue adhesive with biodegradation for wound treatment VCL, LOXL1, SAAL1 SCN4A 4507/4885CYP2D6 4278/4885CYP1A2 4078/4885
US-12585187-B2 Actinic ray-sensitive or radiation-sensitive resin composition, resist film, pattern forming method, method for manufacturing electronic device, and compound RAD51, HAX1, HBG1 SCN4A 4541/4885CYP2D6 4277/4885CYP1A2 3707/4885
US-20260125375-A1 SUBSTITUTED 1H-PYRAZOLO-PYRIDINE AND -PYRIMIDINE COMPOUNDS CCR1, CCR6, CCRL2 SCN4A 1670/4885CYP2D6 132/4885CYP1A2 1039/4885
US-12554196-B2 Actinic ray-sensitive or radiation-sensitive resin composition, pattern forming method, resist film, method for manufacturing electronic device, compound, and method for producing compound RER1, RAD51, GLRA1 SCN4A 3905/4885CYP2D6 3405/4885CYP1A2 3629/4885
US-20220071211-A1 SUBSTITUTED PYRIDINYLOXYBENZENES AND SALTS THEREOF AND USE THEREOF AS HERBICIDAL AGENTS PLPBP, HPD, PNPO SCN4A 3660/4885CYP2D6 251/4885CYP1A2 107/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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