Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6689075 | 0.94 | HTR2C (0.34) | CYP1A2CYP2C9CYP2C19MCHR1HTT | |
| SCHEMBL6693679 | 0.89 | ALDH1A1 (0.33) | HTTALDH1A1KDM4EMAPK1TDP1 | |
| SCHEMBL6691237 | 0.88 | CYP1A2 (0.35) | CYP1A2CYP2C9CYP2C19MCHR1TSHR | |
| SCHEMBL6694183 | 0.83 | CYP1A2 (0.39) | CYP1A2CYP2C9CYP2C19MCHR1TSHR | |
| SCHEMBL6689034 | 0.82 | HTR2C (0.32) | MCHR1HTR2B | |
| SCHEMBL6697903 | 0.81 | CYP1A2 (0.38) | CYP1A2CYP2C9CYP2C19MCHR1TSHR | |
| SCHEMBL6689482 | 0.78 | CYP2C9 (0.35) | CYP1A2CYP2C9CYP2C19MCHR1TP53 | |
| SCHEMBL6690623 | 0.77 | CRHBP (0.34) | CRHBPCRHR2 | |
| SCHEMBL6693175 | 0.77 | MAPT (0.32) | HTTALDH1A1MAPT | |
| SCHEMBL6690930 | 0.75 | TSHR (0.33) | TSHRGAAALDH1A1L3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869016-B1 | Pneumatic radial tires | BRIDGESTONE CORP (JP) | 2004-03-03 | — | — | EP | disclosed |
| US-6336486-B1 | Pneumatic radical tire having cap base tread | BRIDGESTONE CORPORATION (JP) | 2002-01-08 | — | — | US | disclosed |
| EP-0869016-A2 | Pneumatic radial tires | Bridgestone Corporation (JP) | 1998-10-07 | — | — | EP | disclosed |