Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 3/20 | 0.32 |
| ▸ | HTR2C | P28335 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HTR1B | P28222 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6691038 | 0.90 | TSHR (0.33) | TSHRHTR2AHTR2CSMN1; SMN2HTR1B | |
| SCHEMBL6691232 | 0.90 | MEN1 (0.35) | TSHRMAPTNPC1LMNAMEN1 | |
| SCHEMBL6691234 | 0.88 | HTR2A (0.32) | TSHRHRH3HTR2AHTR2CSMN1; SMN2 | |
| SCHEMBL6694327 | 0.82 | RAB9A (0.34) | TSHRHTR2AHTR2CSMN1; SMN2HTR1B | |
| SCHEMBL6693788 | 0.80 | MEN1 (0.35) | TSHRMAPTNPC1LMNAMEN1 | |
| SCHEMBL6693472 | 0.78 | MEN1 (0.33) | MAPTNPC1MEN1ALDH1A1KMT2A | |
| SCHEMBL6697971 | 0.75 | CYP1A2 (0.38) | TSHRHTR2BMAPTLMNAHPGD | |
| SCHEMBL6697903 | 0.75 | CYP1A2 (0.38) | TSHRHTR2BMAPTLMNAHPGD | |
| SCHEMBL6692273 | 0.73 | SNCA (0.40) | SMN1; SMN2MAPTNPC1RAB9ALMNA | |
| SCHEMBL6698691 | 0.72 | HTR2A (0.33) | TSHRHRH3HTR2AHTR2CHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869016-B1 | Pneumatic radial tires | BRIDGESTONE CORP (JP) | 2004-03-03 | — | — | EP | disclosed |
| US-6336486-B1 | Pneumatic radical tire having cap base tread | BRIDGESTONE CORPORATION (JP) | 2002-01-08 | — | — | US | disclosed |
| EP-0869016-A2 | Pneumatic radial tires | Bridgestone Corporation (JP) | 1998-10-07 | — | — | EP | disclosed |