Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.30 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | DUSP1 | P28562 | 1/20 | 0.30 |
| ▸ | DUSP6 | Q16828 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6694762 | 1.00 | BCHE (0.33) | BCHEACHEEPHX1EPHX2RAB9A | |
| Hydrochloric Acid SCHEMBL6836594 | 0.84 | BCHE (0.33) | BCHEACHEP2RX1P2RX3P2RX4 | |
| Hydrochloric Acid SCHEMBL5853033 | 0.80 | HPGD (0.39) | EPHX2RAB9ASMN1; SMN2CYP2C19LMNA | |
| Hydrochloric Acid SCHEMBL5852837 | 0.80 | HPGD (0.39) | EPHX2RAB9ASMN1; SMN2CYP2C19LMNA | |
| Hydrochloric Acid SCHEMBL5853852 | 0.79 | HPGD (0.37) | EPHX2RAB9ASMN1; SMN2CYP2C19LMNA | |
| Hydrochloric Acid SCHEMBL6840561 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL6837860 | 0.76 | SIGMAR1 (0.35) | SMN1; SMN2TP53CYP3A4CYP2D6LMNA | |
| Hydrochloric Acid SCHEMBL5853720 | 0.75 | SIGMAR1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL5853701 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL217385 | 0.73 | HTR6 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004106394-A1 | COPOLYMERS OF ETHYLENE AND/OR α-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-12-09 | — | — | WO | disclosed |