⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL932016 | 0.92 | — | — | |
| SCHEMBL10535505 | 0.90 | LMNA (0.59) | — | |
| SCHEMBL10535502 | 0.90 | LMNA (0.59) | — | |
| SCHEMBL31607448 | 0.89 | LMNA (0.43) | — | |
| SCHEMBL3112474 | 0.89 | LMNA (0.43) | — | |
| SCHEMBL336892 | 0.81 | — | — | |
| SCHEMBL9017128 | 0.79 | LMNA (0.59) | — | |
| SCHEMBL9717073 | 0.79 | LMNA (0.59) | — | |
| SCHEMBL9756796 | 0.79 | LMNA (0.59) | — | |
| Water SCHEMBL15312410 | 0.78 | LMNA (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8283482-B2 | Method for producing cross-coupling compound | KAO CORPORATION (JP) | 2012-10-09 | — | — | US | claimed |
| US-20100048929-A1 | METHOD FOR PRODUCING CROSS-COUPLING COMPOUND | KAO CORPORATION (JP) | 2010-02-25 | — | — | US | claimed |
| EP-2143705-A1 | METHOD FOR PRODUCING CROSS-COUPLING COMPOUND | Kao Corporation (JP) | 2010-01-13 | — | — | EP | claimed |
| US-20250326746-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. | 2025-10-23 | — | — | US | disclosed |
| US-12234231-B2 | EIF4E inhibitors and uses thereof | PIC Therapeutics, Inc. (US) | 2025-02-25 | — | — | US | disclosed |
| EP-4392422-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. (US) | 2024-07-03 | — | — | EP | disclosed |
| CN-118103368-A | EIF4E inhibitors and uses thereof | 皮克医疗公司 | 2024-05-28 | — | — | CN | disclosed |
| US-20230150997-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. | 2023-05-18 | — | — | US | disclosed |
| WO-2023028235-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. (US) | 2023-03-02 | — | — | WO | disclosed |
| US-20120258938-A1 | Enzymatic Production or Chemical Synthesis and Uses for 5,7-Dienes and UVB Conversion Products Thereof | SLOMINSKI ANDREJ (US) | 2012-10-11 | — | — | US | disclosed |
| US-8283482-B2 | Method for producing cross-coupling compound | KAO CORPORATION (JP) | 2012-10-09 | — | — | US | disclosed |
| EP-1656141-B1 | TREATMENT FOR ALZHEIMER S DISEASE AND RELATED CONDITIONS | MERCK SHARP & DOHME (GB) | 2010-04-14 | — | — | EP | disclosed |
| US-20100048929-A1 | METHOD FOR PRODUCING CROSS-COUPLING COMPOUND | KAO CORPORATION (JP) | 2010-02-25 | — | — | US | disclosed |
| EP-2143705-A1 | METHOD FOR PRODUCING CROSS-COUPLING COMPOUND | Kao Corporation (JP) | 2010-01-13 | — | — | EP | disclosed |
| US-20080153817-A1 | Treatment for Alzheimer's Disease and Related Conditions | MERCK SHARP & DOHME LTD. (GB) | 2008-06-26 | — | — | US | disclosed |
| EP-1656141-A1 | TREATMENT FOR ALZHEIMER S DISEASE AND RELATED CONDITIONS | MERCK SHARP & DOHME LTD. (GB) | 2006-05-17 | — | — | EP | disclosed |
| WO-2005013985-A1 | TREATMENT FOR ALZHEIMER'S DISEASE AND RELATED CONDITIONS | MERCK SHARP & DOHME LIMITED (GB) | 2005-02-17 | — | — | WO | disclosed |
| EP-1124804-A1 | PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE BIOSYNTHESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000024719-A1 | PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE BIOSYNTHESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2000-05-04 | — | — | WO | disclosed |
| EP-0307115-A1 | Phenol esters | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-03-15 | — | — | EP | disclosed |