Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 20/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5202477 | 0.89 | HTR6 (0.69) | HTR6 | |
| SCHEMBL5203017 | 0.87 | HTR6 (0.77) | HTR6 | |
| SCHEMBL1136470 | 0.87 | HTR6 (1.00) | HTR6 | |
| Hydrochloric Acid SCHEMBL5201686 | 0.86 | HTR6 (0.76) | HTR6 | |
| SCHEMBL5201073 | 0.83 | HTR6 (0.78) | HTR6 | |
| SCHEMBL5203694 | 0.83 | HTR6 (0.85) | HTR6 | |
| Hydrochloric Acid SCHEMBL5763558 | 0.82 | HTR6 (0.76) | HTR6 | |
| SCHEMBL5201153 | 0.82 | HTR6 (0.69) | HTR6 | |
| SCHEMBL5202224 | 0.82 | HTR6 (0.69) | HTR6 | |
| SCHEMBL6698850 | 0.82 | HTR6 (0.63) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040242589-A1 | 3-arylsulfonyl-7-piperzinyl-indoles-benzofurans and -benzothiophenes with 5-ht6 receptor affinity for treating cns disorders | SMITHKLINE BEECHAM PLC (GB) | 2004-12-02 | — | — | US | claimed |
| US-20040242589-A1 | 3-arylsulfonyl-7-piperzinyl-indoles-benzofurans and -benzothiophenes with 5-ht6 receptor affinity for treating cns disorders | SMITHKLINE BEECHAM PLC (GB) | 2004-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242589-A1 | 3-arylsulfonyl-7-piperzinyl-indoles-benzofurans and -benzothiophenes with 5-ht6 receptor affinity for treating cns disorders | HTR6, HTR7, HTR1A | HTR6 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.