Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 6/20 | 0.45 |
| ▸ | DRD3 | P35462 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6696545 | 0.76 | DRD2 (0.50) | SLC6A4DRD2KDM4ELMNAHTR1A | |
| SCHEMBL6692557 | 0.74 | SLC6A4 (0.50) | SLC6A4SLC6A2SLC6A3DRD2DRD3 | |
| SCHEMBL7011761 | 0.68 | SLC6A4 (0.44) | SLC6A4SLC6A2SLC6A3DRD2LMNA | |
| SCHEMBL21064546 | 0.68 | RAB9A (0.43) | SLC6A4SLC6A2SLC6A3LMNA | |
| SCHEMBL1687708 | 0.68 | ALOX5 (0.43) | SLC6A4SLC6A2SLC6A3LMNA | |
| SCHEMBL31240335 | 0.67 | DRD2 (0.45) | SLC6A4SLC6A2DRD2DRD3HTR1A | |
| SCHEMBL14722474 | 0.67 | CYP1A2 (0.57) | SLC6A4SLC6A2DRD3MC4R | |
| SCHEMBL14776011 | 0.67 | SLC6A2 (0.70) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL14775427 | 0.67 | SLC6A2 (1.00) | SLC6A4SLC6A2SLC6A3LMNA | |
| SCHEMBL8233335 | 0.67 | ALOX5 (0.46) | SLC6A4SLC6A2SLC6A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004082686-A2 | USE OF COMPOUNDS WITH COMBINED 5-HT1A AND SSRI ACTIVITIES TO TREAT SEXUAL DYSFUNCTION | DYNOGEN PHARMACEUTICALS, INC. (US) | 2004-09-30 | — | — | WO | claimed |
| WO-2004082686-A2 | USE OF COMPOUNDS WITH COMBINED 5-HT1A AND SSRI ACTIVITIES TO TREAT SEXUAL DYSFUNCTION | DYNOGEN PHARMACEUTICALS, INC. (US) | 2004-09-30 | — | — | WO | disclosed |