Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | PPIB | P23284 | 1/20 | 0.41 |
| ▸ | PPIA | P62937 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | DGAT2 | Q96PD7 | 2/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5234961 | 0.87 | KDM1A (0.41) | GPR88KDM1AMAOBFFAR4NPC1 | |
| SCHEMBL22721277 | 0.80 | GPR88 (0.48) | GPR88KDM1AMAOBFFAR4MAPT | |
| SCHEMBL6698943 | 0.77 | HRH3 (0.42) | KDM1AMAOBNPC1MAPTRAB9A | |
| SCHEMBL18984237 | 0.77 | FFAR1 (0.50) | GPR88KDM1AMAOBFFAR4EPHX2 | |
| SCHEMBL21501071 | 0.77 | FFAR1 (0.50) | GPR88KDM1AMAOBFFAR4EPHX2 | |
| SCHEMBL23425328 | 0.77 | FFAR1 (0.50) | GPR88KDM1AMAOBFFAR4EPHX2 | |
| SCHEMBL6997931 | 0.77 | FFAR1 (0.50) | GPR88KDM1AMAOBFFAR4EPHX2 | |
| SCHEMBL7659702 | 0.77 | FFAR1 (0.50) | GPR88KDM1AMAOBFFAR4EPHX2 | |
| SCHEMBL27699503 | 0.76 | GPR88 (0.43) | GPR88KDM1AMAOBNPC1MAPT | |
| SCHEMBL8084094 | 0.72 | GAA (0.51) | MAPTEPHX2AURKATPX2TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040077881-A1 | $G(d)1-pyrrolines used in pest control | PLANT ANDREW (GB) | 2004-04-22 | — | — | US | disclosed |
| EP-1368311-A1 | DELTA1 -PYRROLINES USED IN PEST CONTROL | Bayer CropScience AG (DE) | 2003-12-10 | — | — | EP | disclosed |
| WO-2002064561-A1 | $G(D)1-PYRROLINES USED IN PEST CONTROL | BAYER CROPSCIENCE AG (DE) | 2002-08-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077881-A1 | $G(d)1-pyrrolines used in pest control | GRM1, DDT, GRIA1 | GPR88 3233/4885KDM1A 1423/4885MAOB 2311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.