SCHEMBL6698583

SCHEMBL6698583

Cc1c(C)c(C)c2c(c1C)Cc1ccccc1O2

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.52
MAOB P27338 1/20 0.52
MAPKAPK2 P49137 1/20 0.38
GAA P10253 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
CYP1A1 P04798 2/20 0.33
AHR P35869 1/20 0.32
NPC1 O15118 1/20 0.31
LMNA P02545 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
PTGS2 P35354 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30066724 0.83 MAOA (0.46) MAOAMAOBMAPKAPK2GAANPSR1
SCHEMBL11981456 0.78 MAOA (0.52) MAOAMAOBMAPKAPK2GAANPSR1
SCHEMBL11297104 0.77 MAOA (0.40) MAOAMAOBMAPKAPK2
SCHEMBL2312346 0.76 MAOA (0.54) MAOAMAOBMAPKAPK2GAANPSR1
SCHEMBL30203186 0.76 MAOA (0.54) MAOAMAOBMAPKAPK2GAANPSR1
SCHEMBL11127249 0.75 MAOA (0.53) MAOAMAOBMAPKAPK2GAANPSR1
SCHEMBL31696794 0.73 MAOA (0.56) MAOAMAOBMAPKAPK2GAANPSR1
SCHEMBL367138 0.73 MAOA (0.55) MAOAMAOBMAPKAPK2GAANPSR1
SCHEMBL29490369 0.73 MAOA (0.55) MAOAMAOBMAPKAPK2GAANPSR1
SCHEMBL28974754 0.73 CYP1A2 (0.43) MAOAMAOBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111303183-A Synthetic method of tetracarboxylic dianhydride with fluorinated rigid structure 浙江中科玖源新材料有限公司 2020-06-19 CN claimed
US-12091507-B2 Polymers for use in electronic devices DUPONT ELECTRONICS, INC. (US) 2024-09-17 US disclosed
CN-112424261-A Polymers for use in electronic devices 杜邦电子公司 2021-02-26 CN disclosed
US-20210017335-A1 Polymers For Use In Electronic Devices U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2021-01-21 US disclosed
CN-111303183-A Synthetic method of tetracarboxylic dianhydride with fluorinated rigid structure 浙江中科玖源新材料有限公司 2020-06-19 CN disclosed
WO-2019195148-A1 POLYMERS FOR USE IN ELECTRONIC DEVICES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2019-10-10 WO disclosed
JP-2004244381-A METHOD FOR PRODUCING 9,9-DIMETHYLXANTHENE DICARBOXYLIC ACID SEIMI CHEM CO LTD 2004-09-02 JP disclosed
EP-0738723-B1 Method for making polyalkylated xanthenes GEN ELECTRIC (US) 2002-03-13 EP disclosed
EP-0738723-A2 Method for making polyalkylated xanthenes GENERAL ELECTRIC COMPANY (US) 1996-10-23 EP disclosed
US-5554770-A Method for making polyalkylated xanthenes GENERAL ELECTRIC COMPANY (US) 1996-09-10 US disclosed
US-5430199-A Method for recovering phenol and xanthene values from bisphenol A tars GENERAL ELECTRIC COMPANY (US) 1995-07-04 US disclosed