SCHEMBL28974754

SCHEMBL28974754

Cc1c(C)c(C)c2c(c1C)Cc1ccccc1C2

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.43
DRD2 P14416 5/20 0.41
DRD1 P21728 5/20 0.41
DRD5 P21918 5/20 0.41
DRD3 P35462 5/20 0.41
DRD4 P21917 2/20 0.41
CYP2A6 P11509 1/20 0.37
TSHR P16473 2/20 0.35
MAOA P21397 2/20 0.35
MAOB P27338 1/20 0.35
ALOX15 P16050 1/20 0.34
HSD17B10 Q99714 1/20 0.34
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
PNMT P11086 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14800405 0.82 NQO1 (0.38) CYP1A2DRD2DRD1DRD5DRD3
SCHEMBL6904545 0.78 CYP1A2 (0.43) CYP1A2DRD2DRD1DRD5DRD3
SCHEMBL23739814 0.74 CYP1A2 (0.40) CYP1A2DRD2DRD1DRD5DRD3
SCHEMBL1790495 0.73 CYP1A2 (0.50) CYP1A2DRD2DRD1DRD5DRD3
SCHEMBL6698583 0.73 MAOA (0.52) MAOAMAOBSMN1; SMN2
SCHEMBL1192279 0.72 DRD2 (0.41) CYP1A2DRD2DRD1DRD5DRD3
SCHEMBL8666004 0.72 CYP1A2 (0.56) CYP1A2DRD2DRD1DRD5DRD3
SCHEMBL15960870 0.71 MAOA (0.53) CYP1A2TSHRMAOAMAOBALDH1A1
SCHEMBL31589075 0.71 MAOA (0.53) CYP1A2TSHRMAOAMAOBALDH1A1
SCHEMBL22081972 0.71 CYP1A2 (0.62) CYP1A2DRD2DRD1DRD5DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114075191-B Organic electroluminescent material, electronic element, and electronic device 陕西莱特光电材料股份有限公司 2023-04-25 CN claimed
CN-116018338-A Novel compound and organic light emitting device comprising the same 株式会社LG化学 2023-04-25 CN disclosed
CN-114075191-B Organic electroluminescent material, electronic element, and electronic device 陕西莱特光电材料股份有限公司 2023-04-25 CN disclosed
CN-115894535-A Polycyclic aromatic compound, multimer thereof, material for organic device, organic electroluminescent element, and application thereof 学校法人关西学院 2023-04-04 CN disclosed
CN-115746032-A Polycyclic aromatic compound, material for organic device, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2023-03-07 CN disclosed
CN-115703803-A Polycyclic aromatic compound, material for organic device, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2023-02-17 CN disclosed