SCHEMBL6698586

SCHEMBL6698586

Cc1cc2c(c(C)c1C)C(C)c1ccccc1O2

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
TP53 P04637 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ALDH1A1 P00352 2/20 0.37
MAPT P10636 2/20 0.37
HTT P42858 1/20 0.37
GRM2 Q14416 1/20 0.36
ATM Q13315 1/20 0.35
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
USP2 O75604 1/20 0.34
FFAR4 Q5NUL3 1/20 0.34
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
HRH1 P35367 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11127247 0.81 MAOA (0.41) MAOAMAOBTP53L3MBTL1HTT
SCHEMBL367139 0.77 GRM2 (0.44) MAOAMAOBTP53L3MBTL1MAPT
SCHEMBL436702 0.75 MAOA (0.58) MAOAMAOBTP53L3MBTL1MAPT
SCHEMBL29797921 0.75 MAOA (0.58) MAOAMAOBTP53L3MBTL1MAPT
SCHEMBL1241287 0.72 TP53 (0.36) MAOAMAOBTP53L3MBTL1HTT
SCHEMBL12205445 0.70 KMT2A (0.46) MAOAMAOBTP53L3MBTL1ALDH1A1
SCHEMBL10967593 0.70 MAOA (0.46) MAOAMAOBTP53L3MBTL1MAPT
SCHEMBL6599505 0.70 GRM2 (0.37) MAOAMAOBTP53MAPTHTT
SCHEMBL29289989 0.69 GRM2 (0.43) MAOAMAOBL3MBTL1MAPTGRM2
SCHEMBL26292428 0.67 AHR (0.41) MAOAMAOBTP53HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111303183-A Synthetic method of tetracarboxylic dianhydride with fluorinated rigid structure 浙江中科玖源新材料有限公司 2020-06-19 CN claimed
US-12091507-B2 Polymers for use in electronic devices DUPONT ELECTRONICS, INC. (US) 2024-09-17 US disclosed
CN-112424261-A Polymers for use in electronic devices 杜邦电子公司 2021-02-26 CN disclosed
US-20210017335-A1 Polymers For Use In Electronic Devices U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2021-01-21 US disclosed
CN-111303183-A Synthetic method of tetracarboxylic dianhydride with fluorinated rigid structure 浙江中科玖源新材料有限公司 2020-06-19 CN disclosed
WO-2019195148-A1 POLYMERS FOR USE IN ELECTRONIC DEVICES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2019-10-10 WO disclosed
JP-2004244381-A METHOD FOR PRODUCING 9,9-DIMETHYLXANTHENE DICARBOXYLIC ACID SEIMI CHEM CO LTD 2004-09-02 JP disclosed
EP-0738723-B1 Method for making polyalkylated xanthenes GEN ELECTRIC (US) 2002-03-13 EP disclosed
EP-0738723-A2 Method for making polyalkylated xanthenes GENERAL ELECTRIC COMPANY (US) 1996-10-23 EP disclosed
US-5554770-A Method for making polyalkylated xanthenes GENERAL ELECTRIC COMPANY (US) 1996-09-10 US disclosed
US-5430199-A Method for recovering phenol and xanthene values from bisphenol A tars GENERAL ELECTRIC COMPANY (US) 1995-07-04 US disclosed