SCHEMBL1241287

SCHEMBL1241287

Cc1cc(CC(C)C)cc2c1C(C)c1ccccc1O2

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.36
L3MBTL1 Q9Y468 4/20 0.34
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
PRMT1 Q99873 1/20 0.33
GRM2 Q14416 1/20 0.32
BCHE P06276 1/20 0.32
ACHE P22303 1/20 0.32
KMT2A Q03164 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22834295 0.80 BCHE (0.37) L3MBTL1MAOAMAOBPRMT1BCHE
SCHEMBL8021072 0.80 BCHE (0.37) L3MBTL1MAOAMAOBPRMT1BCHE
SCHEMBL7509519 0.74 GABRA1 (0.40) L3MBTL1MAOAMAOBPRMT1GRM2
SCHEMBL367139 0.73 GRM2 (0.44) TP53L3MBTL1MAOAMAOBGRM2
SCHEMBL6698586 0.72 MAOA (0.40) TP53L3MBTL1MAOAMAOBGRM2
SCHEMBL308808 0.69 MAOA (0.43) MAOAMAOBBCHEACHE
SCHEMBL29797921 0.68 MAOA (0.58) TP53L3MBTL1MAOAMAOBKMT2A
SCHEMBL436702 0.68 MAOA (0.58) TP53L3MBTL1MAOAMAOBKMT2A
SCHEMBL25883003 0.68 AHR (0.44) BCHEACHE
SCHEMBL11127247 0.67 MAOA (0.41) TP53L3MBTL1MAOAMAOBGRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250011721-A1 COMPOSITIONS AND METHODS FOR IMPLANTATION OF PROCESSED ADIPOSE TISSUE AND PROCESSED ADIPOSE TISSUE PRODUCTS THE JOHNS HOPKINS UNIVERSITY 2025-01-09 US disclosed
US-20220073881-A1 COMPOSITIONS AND METHODS FOR IMPLANTATION OF PROCESSED ADIPOSE TISSUE AND PROCESSED ADIPOSE TISSUE PRODUCTS THE JOHNS HOPKINS UNIVERSITY 2022-03-10 US disclosed
US-11078461-B2 Compositions and methods for implantation of processed adipose tissue and processed adipose tissue products THE JOHNS HOPKINS UNIVERSITY (US) 2021-08-03 US disclosed
US-20180127719-A1 COMPOSITIONS AND METHODS FOR IMPLANTATION OF PROCESSED ADIPOSE TISSUE AND PROCESSED ADIPOSE TISSUE PRODUCTS THE JOHNS HOPKINS UNIVERSITY 2018-05-10 US disclosed
US-20120189588-A1 Compositions and Methods for Implantation of Processed Adipose Tissue and Processed Adipose Tissue Products THE JOHNS HOPKINS UNIVERSITY (US) 2012-07-26 US disclosed
CN-102575229-A Compositions and methods for implantation of processed adipose tissue and processed adipose tissue products UNIV JOHNS HOPKINS 2012-07-11 CN disclosed
EP-2464724-A2 COMPOSITIONS AND METHODS FOR IMPLANTATION OF PROCESSED ADIPOSE TISSUE AND PROCESSED ADIPOSE TISSUE PRODUCTS The Johns Hopkins University (US) 2012-06-20 EP disclosed
WO-2011019822-A2 COMPOSITIONS AND METHODS FOR IMPLANTATION OF PROCESSED ADIPOSE TISSUE AND PROCESSED ADIPOSE TISSUE PRODUCTS THE JOHNS HOPKINS UNIVERSITY (US) 2011-02-17 WO disclosed