Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL1115493 | 0.95 | CA4 (0.39) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL15283203 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL301926 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL9576627 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL13725826 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL6253608 | 0.91 | CA4 (0.36) | CA4CA1FAHD1 | |
| Bicarbonate SCHEMBL2050659 | 0.89 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL8359062 | 0.89 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL81419 | 0.89 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL2304976 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117004094-B | Starch-based foaming composition, starch-based foaming product and preparation method thereof | 河南奥尼斯帝新材料有限公司 | 2024-08-02 | — | — | CN | disclosed |
| CN-117004094-A | Starch-based foaming composition, starch-based foaming product and preparation method thereof | 河南奥尼斯帝新材料有限公司 | 2023-11-07 | — | — | CN | disclosed |
| EP-2606093-A1 | HEAT STABLE HALOGEN-FREE FLAME RETARDANT COPOLYESTER THERMOPLASTIC ELASTOMER COMPOSITIONS | E.I. Du Pont De Nemours And Company (US) | 2013-06-26 | — | — | EP | disclosed |
| US-8415415-B2 | Heat stable halogen-free flame retardant copolyester thermoplastic elastomer compositions | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-04-09 | — | — | US | disclosed |
| US-20120211256-A1 | HEAT STABLE HALOGEN-FREE FLAME RETARDANT COPOLYESTER THERMOPLASTIC ELASTOMER COMPOSITIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-08-23 | — | — | US | disclosed |
| WO-2012024280-A1 | HEAT STABLE HALOGEN-FREE FLAME RETARDANT COPOLYESTER THERMOPLASTIC ELASTOMER COMPOSITIONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-02-23 | — | — | WO | disclosed |