Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HCAR3 | P49019 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | NNMT | P40261 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6700940 | 0.85 | NNMT (0.59) | HCAR3HCAR2NNMT | |
| SCHEMBL24774175 | 0.84 | MAPK1 (0.51) | MAPK1HCAR3KDM4EL3MBTL1GABRA5 | |
| SCHEMBL29364292 | 0.82 | HCAR3 (0.46) | HCAR3HCAR2NNMT | |
| SCHEMBL6700450 | 0.82 | HCAR3 (0.46) | HCAR3HCAR2NNMT | |
| SCHEMBL692654 | 0.80 | HCAR3 (0.71) | MAPK1HCAR3KDM4EL3MBTL1GABRA5 | |
| SCHEMBL6696009 | 0.79 | HCAR3 (0.42) | HCAR3L3MBTL1HCAR2NNMTMAPT | |
| SCHEMBL13043454 | 0.79 | HCAR3 (0.57) | MAPK1HCAR3KDM4EL3MBTL1GABRA5 | |
| SCHEMBL13739418 | 0.77 | MAPK1 (0.61) | MAPK1HCAR3KDM4EL3MBTL1GABRA5 | |
| SCHEMBL693630 | 0.76 | HCAR3 (0.50) | MAPK1HCAR3KDM4EL3MBTL1GABRA5 | |
| SCHEMBL6984008 | 0.75 | HCAR3 (0.68) | MAPK1HCAR3KDM4EL3MBTL1GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040180925-A1 | Dipeptidylpeptidase-IV inhibitor | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-09-16 | — | — | US | disclosed |
| EP-1354882-A1 | DIPEPTIDYL PEPTIDASE IV INHIBITOR | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-10-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040180925-A1 | Dipeptidylpeptidase-IV inhibitor | DPP4, DPP3, DPP9 | MAPK1 3092/4885HCAR3 1095/4885KDM4E 2945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.