Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 8/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | NNMT | P40261 | 1/20 | 0.37 |
| ▸ | IL1B | P01584 | 1/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6700940 | 0.82 | NNMT (0.59) | HCAR3HCAR2NNMT | |
| SCHEMBL6698754 | 0.79 | MAPK1 (0.50) | HCAR3HCAR2NNMTMAPTL3MBTL1 | |
| SCHEMBL6700450 | 0.78 | HCAR3 (0.46) | HCAR3HCAR2NNMTKMT2A | |
| SCHEMBL29364292 | 0.78 | HCAR3 (0.46) | HCAR3HCAR2NNMTKMT2A | |
| SCHEMBL6700003 | 0.76 | MAPT (0.44) | IL1BNUDT1MAPTKMT2A | |
| SCHEMBL25533215 | 0.75 | NNMT (0.44) | HCAR3HCAR2NNMTMEN1LMNA | |
| SCHEMBL12212102 | 0.74 | NUDT1 (0.39) | HCAR3IL1BNUDT1MEN1LMNA | |
| SCHEMBL1435912 | 0.74 | NPC1 (0.46) | NUDT1MEN1LMNAMAPTKMT2A | |
| SCHEMBL6700607 | 0.74 | PTK2 (0.45) | NUDT1TP53MAPTKMT2AL3MBTL1 | |
| SCHEMBL3827086 | 0.72 | RAB9A (0.51) | IL1BMEN1LMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040180925-A1 | Dipeptidylpeptidase-IV inhibitor | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-09-16 | — | — | US | disclosed |
| EP-1354882-A1 | DIPEPTIDYL PEPTIDASE IV INHIBITOR | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-10-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040180925-A1 | Dipeptidylpeptidase-IV inhibitor | DPP4, DPP3, DPP9 | HCAR3 1095/4885HCAR2 2206/4885NNMT 2846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.