Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.43 |
| ▸ | PPARG | P37231 | 7/20 | 0.43 |
| ▸ | PPARD | Q03181 | 7/20 | 0.43 |
| ▸ | PPARA | Q07869 | 7/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | FABP4 | P15090 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14360113 | 0.89 | ALDH1A1 (0.50) | AKR1B1TSHRGPR84PPARGPPARD | |
| Stearic Acid SCHEMBL8099038 | 0.87 | FFAR4 (0.62) | AKR1B1TSHRGPR84PPARGPPARD | |
| SCHEMBL7386873 | 0.86 | GABRP (0.50) | AKR1B1TSHR | |
| SCHEMBL14359881 | 0.84 | ALDH1A1 (0.47) | AKR1B1TSHRGPR84PPARGPPARD | |
| SCHEMBL9540324 | 0.83 | CYP1A2 (0.43) | AKR1B1TSHRGPR84PPARGPPARD | |
| SCHEMBL7085904 | 0.83 | ALDH1A1 (0.55) | AKR1B1TSHRGPR84PPARGPPARD | |
| SCHEMBL7760623 | 0.83 | LMNA (0.42) | AKR1B1TSHRFFAR4SLC22A6LMNA | |
| SCHEMBL7753403 | 0.82 | FFAR1 (0.61) | AKR1B1TSHRGPR84PPARGPPARD | |
| SCHEMBL5712787 | 0.82 | FFAR1 (0.61) | AKR1B1TSHRGPR84PPARGPPARD | |
| SCHEMBL11037252 | 0.82 | FFAR1 (0.61) | AKR1B1TSHRGPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0110362-B1 | FRAGRANCE AND FLAVOUR COMPOSITIONS | L. GIVAUDAN & CIE Société Anonyme (CH) | 1988-04-20 | — | — | EP | claimed |
| EP-0925792-B1 | Insoluble insulin compositions for controlling blood glucose | LILLY CO ELI (US) | 2004-04-21 | — | — | EP | disclosed |
| EP-1396272-A1 | Insoluble Insulin Compositions for Controlling Blood Glucose | Eli Lilly & Company (US) | 2004-03-10 | — | — | EP | disclosed |
| US-20030144181-A1 | Insoluble compositions for controlling blood glucose | BRADER MARK LAURENCE (US) | 2003-07-31 | — | — | US | disclosed |
| US-6531448-B1 | Composition comprising protein selected from insulin, insulin analog, and proinsulin; derivatized protein selected from fatty acid-acylated insulins; complexing compound; hexamer stabilizing compound; and divalent metal cation | ELI LILLY AND COMPANY | 2003-03-11 | — | — | US | disclosed |
| US-20020082199-A1 | Insoluble insulin compositions | BRADER MARK LAURENCE (US) | 2002-06-27 | — | — | US | disclosed |
| EP-1196445-A1 | INSULIN CRYSTALS FOR PULMONARY ADMINISTRATION | ELI LILLY AND COMPANY (US) | 2002-04-17 | — | — | EP | disclosed |
| EP-1196446-A1 | PROTAMINE-FREE INSOLUBLE ACYLATED INSULIN COMPOSITIONS | ELI LILLY AND COMPANY (US) | 2002-04-17 | — | — | EP | disclosed |
| EP-1173482-A1 | INSULIN CRYSTALS FOR PULMONARY ADMINISTRATION | ELI LILLY AND COMPANY (US) | 2002-01-23 | — | — | EP | disclosed |
| US-20010036916-A1 | Insoluble insulin compositions | BRADER MARK LAURENCE (US) | 2001-11-01 | — | — | US | disclosed |
| WO-2001000674-A1 | INSULIN CRYSTALS FOR PULMONARY ADMINISTRATION | ELI LILLY AND COMPANY (US) | 2001-01-04 | — | — | WO | disclosed |
| WO-2001000675-A1 | PROTAMINE-FREE INSOLUBLE ACYLATED INSULIN COMPOSITIONS | ELI LILLY AND COMPANY (US) | 2001-01-04 | — | — | WO | disclosed |
| WO-2000064940-A1 | INSULIN CRYSTALS FOR PULMONARY ADMINISTRATION | ELI LILLY AND COMPANY (US) | 2000-11-02 | — | — | WO | disclosed |
| WO-1999032116-A1 | INSOLUBLE COMPOSITIONS FOR CONTROLLING BLOOD GLUCOSE | ELI LILLY AND COMPANY (US) | 1999-07-01 | — | — | WO | disclosed |
| EP-0925792-A2 | Insoluble compositions for controlling blood glucose | ELI LILLY AND COMPANY (US) | 1999-06-30 | — | — | EP | disclosed |
| WO-1999021578-A1 | INSOLUBLE INSULIN COMPOSITIONS | ELI LILLY AND COMPANY (US) | 1999-05-06 | — | — | WO | disclosed |
| EP-0911035-A2 | INSOLUBLE INSULIN COMPOSITIONS | ELI LILLY AND COMPANY (US) | 1999-04-28 | — | — | EP | disclosed |