Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.73 |
| ▸ | MAOA | P21397 | 6/20 | 0.73 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | BCHE | P06276 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | AR | P10275 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.66 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
| ▸ | MYOC | Q99972 | 1/20 | 0.66 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.64 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25243464 | 1.00 | MAOB (0.73) | MAOBMAOAHSP90AA1MAPTBCHE | |
| SCHEMBL30384224 | 1.00 | MAOB (0.73) | MAOBMAOAHSP90AA1MAPTBCHE | |
| SCHEMBL6699171 | 1.00 | MAOB (0.73) | MAOBMAOAHSP90AA1MAPTBCHE | |
| SCHEMBL31233113 | 1.00 | MAOB (0.73) | MAOBMAOAHSP90AA1MAPTBCHE | |
| SCHEMBL25207247 | 0.89 | MAOB (0.84) | MAOBMAOAHSP90AA1MAPTBCHE | |
| SCHEMBL25202154 | 0.88 | CYP1A1 (0.64) | MAOBMAOAHSP90AA1MAPTAR | |
| SCHEMBL25202013 | 0.85 | MAOB (0.72) | MAOBMAOAHSP90AA1MAPTCYP2C19 | |
| SCHEMBL30384325 | 0.85 | MAOB (0.72) | MAOBMAOAHSP90AA1MAPTCYP2C19 | |
| SCHEMBL129048 | 0.84 | MAOB (1.00) | MAOBMAOAHSP90AA1MAPTBCHE | |
| SCHEMBL25188844 | 0.84 | MAOB (1.00) | MAOBMAOAHSP90AA1MAPTBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10308624-B2 | Catalytic enantioselective synthesis of 2-aryl chromenes and related phosphoramidite ligands and catalyst compounds | NORTHWESTERN UNIVERSITY (US) | 2019-06-04 | — | — | US | disclosed |
| US-20180099943-A1 | Catalytic Enantioselective Synthesis of 2-Aryl Chromenes and Related Phosphoramidite Ligands and Catalyst Compounds | NORTHWESTERN UNIVERSITY | 2018-04-12 | — | — | US | disclosed |
| US-9840487-B2 | Catalytic enantioselective synthesis of 2-aryl chromenes and related phosphoramidite ligands and catalyst compounds | NORTHWESTERN UNIVERSITY (US) | 2017-12-12 | — | — | US | disclosed |
| US-20170217919-A1 | Catalytic Enantioselective Synthesis of 2-Aryl Chromenes and Related Phosphoramidite Ligands and Catalyst Compounds | NORTHWESTERN UNIVERSITY | 2017-08-03 | — | — | US | disclosed |
| US-9624190-B2 | Catalytic enantioselective synthesis of 2-aryl chromenes and related phosphoramidite ligands and catalyst compounds | NORTHWESTERN UNIVERSITY (US) | 2017-04-18 | — | — | US | disclosed |
| US-20160221982-A1 | Catalytic Enantioselective Synthesis of 2-Aryl Chromenes and Related Phosphoramidite Ligands and Catalyst Compounds | NORTHWESTERN UNIVERSITY | 2016-08-04 | — | — | US | disclosed |
| US-9309217-B2 | Catalytic enantioselective synthesis of 2-aryl chromenes and related phosphoramidite ligands and catalyst compounds | NORTHWESTERN UNIVERSITY (US) | 2016-04-12 | — | — | US | disclosed |
| US-20150315168-A1 | Catalytic Enantioselective Synthesis of 2-Aryl Chromenes and Related Phosphoramidite Ligands and Catalyst Compounds | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-11-05 | — | — | US | disclosed |
| US-20150094331-A1 | QUINOLONE INHIBITORS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 | AUSPEX PHARMACEUTICALS, INC. (US) | 2015-04-02 | — | — | US | disclosed |
| US-20040147597-A1 | Anti-mycobacterium compositions and methods of preparing and using same | ADVANCED LIFE SCIENCES, INC. | 2004-07-29 | — | — | US | disclosed |
| US-6677350-B1 | ADMINISTERING CHALCONE-LIKE VINYLCARBONYL COMPOUNDS TO PREVENT OR TREAT MYCOBACTERIUM INFECTIONS/TUBERCULOSIS | ADVANCED LIFE SCIENCES, INC. | 2004-01-13 | — | — | US | disclosed |
| EP-1217995-A2 | ANTI-MYCOBACTERIUM COMPOSITIONS AND METHODS OF PREPARING AND USING SAME | Advanced Life Sciences Inc. (US) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001021164-A2 | ANTI-MYCOBACTERIUM COMPOSITIONS AND METHODS OF PREPARING AND USING SAME | ADVANCED LIFE SCIENCES, INC. (US) | 2001-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170217919-A1 | Catalytic Enantioselective Synthesis of 2-Aryl Chromenes and Related Phosphoramidite Ligands and Catalyst Compounds | PNP, PPA1, CDS2 | MAOB 927/4885MAOA 971/4885HSP90AA1 4580/4885 |
| US-20150094331-A1 | QUINOLONE INHIBITORS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 | PLA2G12A, PLA2G4A, PLA2G2A | MAOB 547/4885MAOA 476/4885HSP90AA1 2203/4885 |
| US-20160221982-A1 | Catalytic Enantioselective Synthesis of 2-Aryl Chromenes and Related Phosphoramidite Ligands and Catalyst Compounds | PNP, PPA1, CDS2 | MAOB 927/4885MAOA 971/4885HSP90AA1 4580/4885 |
| US-10308624-B2 | Catalytic enantioselective synthesis of 2-aryl chromenes and related phosphoramidite ligands and catalyst compounds | PNP, PPA1, CDS2 | MAOB 927/4885MAOA 971/4885HSP90AA1 4580/4885 |
| US-20150315168-A1 | Catalytic Enantioselective Synthesis of 2-Aryl Chromenes and Related Phosphoramidite Ligands and Catalyst Compounds | PNP, PPA1, CDS2 | MAOB 927/4885MAOA 971/4885HSP90AA1 4580/4885 |
| US-20040147597-A1 | Anti-mycobacterium compositions and methods of preparing and using same | IMMT, CYP51A1, LSS | MAOB 1715/4885MAOA 1739/4885HSP90AA1 1235/4885 |
| US-20180099943-A1 | Catalytic Enantioselective Synthesis of 2-Aryl Chromenes and Related Phosphoramidite Ligands and Catalyst Compounds | PNP, PPA1, CDS2 | MAOB 927/4885MAOA 971/4885HSP90AA1 4580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.